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Neuroscience News has been at 3 events

HostFollowersTitleDateGuestsLinks
Science on Google+453,534Isaac Newton's Birthday is on ChristmasJoin us in a Newton-inspired holiday physics hangout with rockstar physicist +Henry Reich of +MinutePhysics and +MinuteEarth  and brilliant ballerina biologist +Carin Bondar of +National Geographic, +Scientific American and host of Wild Sex, a science show about the strange reproductive habits of the animal kingdom. She knows how the world gets physical. +Veritasium  AKA +Derek Muller may pop in.  We hear there may even be more special guests so you should probably go ahead and RSVP yes to join the lively conversation. BYOB. Hosted by +Amy Robinson of +Science on Google+ .Happy Newtonmas Hangout2013-12-19 00:00:00144 
EyeWire279,593+Sebastian Seung, Professor of Computational Neuroscience at +Massachusetts Institute of Technology (MIT) and creator of +EyeWire will host a 30 minute hangout on air on Thursday, Dec 12th at 3 PM US EST. During this hangout, Sebastian will answer questions about scientific discoveries made possible with the help of EyeWirers as well as talk about what's in the works for the future of EyeWire.Hangout with Neuroscientist Sebastian Seung2013-12-12 21:00:0055 
Science on Google+453,534Please join us for a collaborative Hangout On Air with Autism Brainstorm (http://goo.gl/HO5LZL). We will be discussing current research in Autism and Autism Education, as well as the protein biomarkers associated with Autism Spectrum Disorders.Topics: 1) Lead by Dr. +Stephen Shore:  Research in Comparative Approaches to Autism Education with special emphasis on the Miller Method®. Dr. Shore will be joined by Ethan Miller and Amir Naimov for discussion and Q&A.2) Lead by +John Elder Robison:  Current research topic(s) being considered by IACC (The Interagency Autism Coordinating Committee  is a Federal advisory committee charged with coordinating all activities concerning autism spectrum disorder within the U.S.3) Lead by Dr. +Alisa Woods: Protein Biomarkers and Autism Spectrum DisordersPDF LINKS:Dr. Stephen Shore Dissertation: Comparative Approaches to Autism Education: http://goo.gl/lnqpxbDr. Stephen Shore: ICDL The Miller Method: http://goo.gl/X6XQoqJohn Elder Robison: Scholar in Residence at William And Mary: http://goo.gl/QPxtLH John Elder Robison: IACC Government Strategic Plan for Autism Research: http://goo.gl/reBc9aDr. Alisa G Woods: Treating Clients with AS and ASD: http://goo.gl/175424Dr. Alisa G Woods: Proteomics and Cholesterol in Autism: http://goo.gl/SklhcLDr. Stephen Shore:Diagnosed with "Atypical Development and strong autistic tendencies" and "too sick" for outpatient treatment Dr. Shore was recommended for institutionalization. Nonverbal until four, and with much support from his parents, teachers, wife, and others, Stephen is now a professor at Adelphi University where his research focuses on matching best practice to the needs of people with autism.In addition to working with children and talking about life on the autism spectrum, Stephen presents and consults internationally on adult issues pertinent to education, relationships, employment, advocacy, and disclosure as discussed in his books Beyond the Wall: Personal Experiences with Autism and Asperger Syndrome, Ask and Tell: Self-advocacy and Disclosure for People on the Autism Spectrum, the critically acclaimed Understanding Autism for Dummies., and the newly released DVD Living along the Autism Spectrum: What it means to have Autism or Asperger Syndrome.President emeritus of the Asperger’s Association of New England and former board member of the Autism Society, Dr. ShorAutism Brainstorm and Science On Google+ Collaborative Hangout On Air2013-12-10 04:00:0088 

Neuroscience News has been shared in 50 public circles

AuthorFollowersDateUsers in CircleCommentsReshares+1Links
Helpful Mum1,344This is a circle of people who are frequent G+ users. Really interesting to add if you are just getting started out. Feel free to share the circle.2014-05-18 18:35:454928510
Graeme McRae25,726Graeme's Circle of Active GooglePlussers! . . . This is a curated circle of active people on Google+ If you add this circle, you will see hundreds of new posts per day in your stream from this circle alone. If you’re in the circle (you’ll know ‘cause I notified you) then please reshare it! It's a circle of people I started following a few months ago, and who have consistently posted something at least once a week during all of weeks since then. If you want an interesting stream, you should add this circle. If you're interested in how I curated this circle, and why I think it makes for a really great stream, read on. . .How did these people get in the circle?. . . They must have posted something interesting, at least once, because I don't follow people unless they post something interesting. By now, you're probably not surprised by the number of people on G+ whose pages are full of repeated posts, videos without comments, "what's up" and other uninteresting things. I don't follow those people.How did they stay in the circle since they were added?. . . After I add someone, I keep them in the circle of people I added around the same time. Then, several times a week, I go through all my circles and delete people who haven't posted (something visible to me) in the last 7 days. So the people who are left in the circle are consistent posters. That says something important about them, because consistency is a proxy for quality.Wait. What? Why is consistency is a proxy for quality?. . . I'll admit it: I don't have the science to back up that wild statement, but I'll tell you why I believe it to be true. People who post crap don't get a lot of followers, and the few followers they have don't bother to engage. After a while, the crappy-posting people start to think G+ is a ghost town, and they lose interest. On the other hand, the people who share (or re-share) interesting things get followers and engagement, slowly at first, but ever increasing, and this outpouring of love is what keeps them going. That's what I think anyway, and I'm sticking to it.People who share interesting things get lots of followers. . . This is another half-baked theory of mine, but hear me out. You might think this makes sense: Google+ offers suggestions of people to follow, especially to new users. Google+'s only source of names to suggest are other G+ers like yourself. The G+ers who have the most engagement are the ones Google+ knows will be good to follow, so these people get put out as suggestions more often, and some percentage of those suggestions are taken up. So the more engagement you have, the more Google+ will suggest you as a person to follow, and so the more followers you'll get. Completing the theory: the more interesting the stuff you share (or reshare), the more engagement you'll get, and hence the more followers you'll get.How can I get in your circle?. . . Don't bother trying to "get into" this circle. This circle isn't for you to get into. Think of it the other way around. This circle is for you to add, so you can follow a bunch of interesting and consistent people. The stream from this one circle will be chock-full of fascinating content for you to reshare. People will start to notice your reshares, and they will engage with you, and then Google+ will "notice" (it's a computer, but let's anthropomorphise, shall we?) you and suggest you to others, who will then follow you.No, really. How can I get in your circle?. . . First, unfollow me, then wait, oh, about a week. Spend that week posting a shitload of interesting things. Then follow me. Since you're so interesting, Google+ will notify me that you followed me (G+ doesn'2014-05-17 08:06:51492554988
Will Hawkins33,835Google Friends! - You're in this Circle - Share the circle *'"*:•:•* •-::-•:*:•-:¦: Share and Be Shared :¦:-•:*:•.::• •-:•:''''*                                              118This is a super Circle and in it I put together a group of really interesting and active people on Google Plus to add in your circles.I'm talking about the top Google+ users that share unique and original contents.Follow this advice and grow your G+ community with people that share amazing content that will surprise you:Boost your visibility on Google+ - Share the circle!If you want to be added to the next Circle you have to do these simple steps:1 - Include me in your circles 3 - Share the circle (Publicly) 4 - Add +1 to the post 5 - Follow your dreams and smile to life.More you share more you get! :)Thanks!Circle Networkhttps://plus.google.com/b/112542593288160483901/112542593288160483901/postsNetwork Circleshttps://plus.google.com/b/112542593288160483901/communities/113362757071870225795#circles   #circleshare   #circlesharing   #sharedcircles #sharingcircles   #sharedpubliccircles   #sharedcircleoftheday   #share   #shared   #followers   #addcircles #publicsharedcircles   #share   #addpeople   #addcircle #addfriends   #circle  Circlenetwork CircleNetworking IPNetwork NetworkingCircles2014-05-13 22:47:45500534395
Social Media Revolution637All Science! #sharedcircles #sharedpubliccircles #circleshare #circlesharing #circle 2013-08-20 16:03:51189035
Social Media Revolution592Science #circleshare   #sharedcircles  2013-08-10 21:42:081890113
Science é Ciencia0We've been shared by +Science on Google+: A Public Database among other 246 interesting pages related to Science that you can follow here on Google+ adding this circle.Thank you! :D #science   #circles   #circlesharing   #sharedcircles  2013-07-24 10:00:53247001
Smartphones23,919Super Tech Circle Share! #technology   #smartphones   #tablets   #google   #sharedcircles   #publiccircle   #techcircle   #android   #apple   #googleplus   #mobile   #glass   #googleplustips   #socialmedia  2013-05-07 05:26:38104002
Bobo Fett4Those of you flocking here from the horror that is Facebook, or any that have been here for a while, or maybe even never a part of FB, some pointers to get you started.First thing to know if you type a question mark pretty much anywhere (as long as you don't have a text field in focus, in other words a blinking cursor where you would type text) in G+ you get a little pop up that gives you some handy basic keyboard shortcuts.If you are new here and and you are looking to make your feed more active, click the two little circles labeled Find people in the icons down the left side of the G+ page.  There you can search for people you know and add them to your circles.  Circles are what G+ uses to allow you to organize your friends list.  G+ starts you off with a few default Circles to use, you just need to add people and/or pages to things you enjoy to one of those circles.  Once you have you will see grey buttons at the top of your main feed (The page you get to if you click the big Google+ icon in the top left hand corner).  The first button is the default All circles button, here you will see all of the posts of every person/page you have added to any of your circles.  Next to the All button you will see buttons with the names of your circles.  If you click one of them you will of course see just posts from people/pages in that circle, but also on the rightish side, not quite at the top of the page, you will find a button that says Settings.  That is a drop down that gives you two check boxes.  One is "Show posts in home stream" the other is "Get Notified of new posts".  They pretty much do what they say, and "get notified" means any posts from this circle will make the number between your name and the + Share button in the top right hand corner increment and go red.  You can click that number at any time (even if it's red and 0) to get a drop down window which will show a condensed version of all posts from circles you get notified about. It will also notify you any time someone circles you back, and any +1s you have received in posts or comments you have made. As well as, comments in posts you have also commented on. On this Settings button you will also see a grey area that says Amount.  If you hover over that you get to choose More, Standard, or Fewer.  Which controls how frequently the posts from that circle appear in your feed.If you combine the above tools with the fact that you can change the name of any circle, add as many as you like, and also have people in more than one circle, you have very granular control over what posts you see and when, and exactly who can see your posts.  You can also share your circles with other people, as I have done below.  If you click the View shared circle button below, you will be able to see all the pages in a circle I call, go figure, Pages.  You can look through it and if you like everything you can just add the whole circle as a new circle.  Or, you can pick and choose which things you find interesting and add just them to your own circle that you already have or create a new circle.  Moving stuff from circle to circle is as easy and dragging the rectangle for that particular page/person and dropping onto the circle you want it to be in.  You could also just add this circle in full and then just delete the stuff you don't want (little x in top right hand corner of each rectangle when you hover over it).  Or just view this circle to get ideas for what sort of stuff can be searched for, and use the search box at the top of the Find people/Circle page to find stuff you like.Now once you have some friends added to circles, and pages/people you would like to follow added as well, your feed will get much more interesting. Now on to posting your own stuff.  In the Share what's new... field at the top of pages, you can of course type anything you like2013-05-03 19:55:12143001
Science on Google+60,330Science Pages- All DisciplinesView pages categorized by discipline: http://goo.gl/WCohTLinks to shared science circles: http://goo.gl/nO7rBIf you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database by filling out this form (http://goo.gl/yEg7M). Active profiles and pages will be included in the next shared circle.Science on Google+ community: http://goo.gl/mTTxX#sciencesunday #science #publiccircles #sharedcircles 2013-03-17 13:29:4424071916
Justin Fournier534Tech Engage CircleHello Everyone just following the footsteps of +martin shervington  and attempting to circle share fully engaged circles with you.  Below I'm sharing a circle of definite Technology posters. If your new to this platform and needed a circle for sure fire tech news and help.  *Be sure to add and re-share this circle.*  Later Guys!2013-03-10 16:15:55296516
Science on Google+32,183Science Pages- All DisciplinesView pages categorized by discipline: http://goo.gl/WCohTLinks to shared circles: http://goo.gl/nO7rBAdd your science page to next circle: http://goo.gl/yEg7MScience on Google+ community: http://goo.gl/mTTxX #scienceeveryday  #science #publiccircles #sharedcircles 2013-02-08 02:05:592341310
Science on Google+13,921Ultimate Science Page CircleSpice up your stream with this nice set of Science Pages!Join the Science on Google+ Community: http://goo.gl/uhJCNApplied and Mathematical Sciences: http://goo.gl/l0prdNatural Sciences: http://goo.gl/t8ljmSocial Sciences and Communication: http://goo.gl/vqyNSAdd your Profile/Page to Science on Google+: A Public Database If you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database by filling out this form (http://goo.gl/yEg7M). Please note that Profiles also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles .#scienceeveryday   #science   #publiccircles   #sharedcircles2012-12-16 17:10:4039321917
Daniel Harrington26,455SCIENCE TECHNOLOGY CIRCLE! #science   #tech   #sharedcircles   #circleshare   #sciencecircle   #googleplus  2012-12-13 02:01:55106014
Chris Row1,476Time to share again. Here is a good Circle of active people I have shared this one in the past, but in case you missed it here you go.2012-12-06 22:32:02491617
Chris Row1,468Here is a random circle I would like to share with you. just a bunch of random people. give it a shot you never know who you might find it here. add it, share it, enjoy it.2012-12-04 20:14:284919412
Science on Google+12,997Ultimate Science Page Circle 11.20Spice up your stream with this set of Science Pages! Did we miss your science page? Read below.Add your Profile/Page to Science on Google+: A Public Database If you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database by filling out this form (http://goo.gl/yEg7M). Please note that Profiles also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.#scienceeveryday   #science   #publiccircles   #sharedcircles2012-11-20 19:05:1839031112
Science on Google+12,836Ultimate Science Page Circle 11.10Spice up your stream with this set of Science Pages! Nine pages were added this week (see below if you would like to add your science page to the circle).Add your Profile/Page to Science on Google+: A Public Database If you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database by filling out this form (http://goo.gl/yEg7M). Please note that Profiles also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.#scienceeveryday  #science  #publiccircles  #sharedcircles  2012-11-10 13:37:5338201223
Science on Google+12,642Ultimate Science Page CircleSpice up your stream by adding this really nice set of Science Pages! Add your Profile/Page to +Science on Google+: A Public Database If you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database by filling out this form (http://goo.gl/yEg7M). Please note that Profiles also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.#sciencesunday #science #publiccircles #sharedcircles  2012-11-04 00:18:5037321930
Science on Google+11,818Science Page Circle - 10.9.12This is a really nice set of Science Pages!  Approximately 200 pages are in +Science on Google+: A Public Database (see http://goo.gl/WCohT for a categorized list), and we circled 157 Science Pages in the last two days!!! Check out the new pages by adding this circle and don't forget to share it with your friends!If you received a direct notification about this circle and would like to be added to future circles, please fill out this form: http://goo.gl/yEg7M. Thanks in advance! #scienceeveryday #science #publiccircles #sharedcircles  2012-10-10 01:01:2036524650
Science on Google+11,317Science Pages- All DisciplinesView pages in this circle: http://goo.gl/WCohTView all shared circles: http://goo.gl/nO7rBIf you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/yEg7M). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.#sciencesunday #science #publiccircles #sharedcircles 2012-09-30 12:55:041990917
Scott Sneddon0In the spirit of circle-sharing on #sciencesunday here's my science media circle (a work in progress, but please feel free to add yours and re-share. Let me know what I've missed, or if you have a source you think I should add.Thanks,2012-09-23 15:37:3623103
Science on Google+9,957Psychology and Neuroscience PagesView pages in this circle: http://goo.gl/MwpSt. View all shared circles: http://goo.gl/nO7rBIf you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/yEg7M). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.#sciencesunday #science #publiccircles #sharedcircles 2012-09-21 11:07:33366118
Science on Google+9,821Science Pages- All DisciplinesView pages in this circle: http://goo.gl/WCohTView all shared circles: http://goo.gl/nO7rBIf you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/yEg7M). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.#sciencesunday #science #publiccircles #sharedcircles 2012-09-16 15:43:301944511
Science on Google+9,289Science Pages- All DisciplinesThis is a really nice set of Science Pages (see http://goo.gl/WCohT for a categorized list). Help spread the love of Science by sharing this circle with your friends.If you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/yEg7M). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.#sciencesunday #science #publiccircles #sharedcircles  2012-09-08 14:08:4719364760
Science on Google+9,127Biology and Neuroscience PagesView pages in this circle: http://goo.gl/ctxgwView all shared circles: http://goo.gl/nO7rBIf you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/yEg7M). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.#sciencesunday #science #publiccircles #sharedcircles 2012-09-01 12:45:324201015
Science on Google+8,449Psychology and Neuroscience PagesView pages in this circle: http://goo.gl/MwpSt. View all shared circles: http://goo.gl/nO7rBIf you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/yEg7M). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.#sciencesunday #science #publiccircles #sharedcircles 2012-08-16 00:12:19360414
Science on Google+8,407Biology and Neuroscience PagesView pages in this circle: http://goo.gl/ctxgw.View all shared circles: http://goo.gl/nO7rBIf you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/yEg7M). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.#sciencesunday #science #publiccircles #sharedcircles 2012-08-15 23:55:20422110
Science on Google+7,163Searching for Active Science Pages+Science on Google+: A Public Database currently has 150 science pages in the database (see http://goo.gl/WCohT for a categorized list); however, there are many science pages on G+ that are not in the database. We would like to double this Science Page circle and share it this Sunday for   #sciencesunday ; however, we need your help. If you are curating a science page or know of an active science page that is not in the database (http://goo.gl/WCohT), please add it to the database by filling out this short form: http://goo.gl/yEg7M. We will take all of the active science pages, put them in this circle, and share it this Sunday. When you are done adding your favorite science pages, please share this post so we can reach our 300 page goal by Sunday.  Thanks!2012-07-11 15:21:1915032010
Science on Google+5,678Science Pages- All DisciplinesClick on the following link to view the pages in this circle: http://goo.gl/WCohT. If you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/yEg7M). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.View underlying database: http://goo.gl/Yz8KRView most recent shared circles: http://goo.gl/nO7rB#sciencesunday #science #publiccircles #sharedcircles 2012-06-17 16:02:371404119
Science on Google+5,678Biology and Neuroscience PagesClick on the following link to view the pages in this circle: http://goo.gl/ctxgw.If you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/yEg7M). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.View underlying database: http://goo.gl/Yz8KRView most recent shared circles: http://goo.gl/nO7rB#sciencesunday #science #publiccircles #sharedcircles 2012-06-17 15:05:40321310
The Web Resources0Brand Page Circle..Open to suggestionsTags #sharedcircles   #brandpagecircles   #circlesharing   #Brandpages  +Best Shared Circle +Shared Circles Shared a Circle with You +Reshare +Reshare +SharedCircles +Shared Pages Circles +Shared Circles on G+ +Shared a circle with you ..2012-06-11 23:41:37258053
Science on Google+5,521Updated Science Page Circle 6/10- All DisciplinesClick on the following link to view the pages in this circle: http://goo.gl/WCohT. If you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/yEg7M). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.View underlying database: http://goo.gl/Yz8KRView most recent shared circles: http://goo.gl/nO7rB#sciencesunday #science #publiccircles  #sharedcircles 2012-06-10 17:14:351392169
Science on Google+5,446Science Pages- All DisciplinesClick on the following link to view the pages in this circle: http://goo.gl/WCohT. If you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/yEg7M). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.View underlying database: http://goo.gl/Yz8KRView most recent shared circles: http://goo.gl/nO7rB#sciencesunday #science #publiccircles #sharedcircles 2012-06-03 18:55:35136189
Science on Google+5,446Biology and Neuroscience PagesClick on the following link to view the pages in this circle: http://goo.gl/ctxgw.If you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/yEg7M). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.View underlying database: http://goo.gl/Yz8KRView most recent shared circles: http://goo.gl/nO7rB#sciencesunday #science #publiccircles  #sharedcircles 2012-06-03 18:12:5430115
TheFanar.com Holiday Homes919#CircleSunday #sharedcircles special unique circle continuesravel and Holidays Business PagesThis circle includes the pages of some of the most successful companies in the worldBusiness Pages , Directory for Pages shared , Shared Pages , Shared Business Pages , Directory for Pages , G+ Shared Circle Directory for Pages#hoildays #travel #directory #sharedcircles #busniess #smes #news2012-05-22 13:30:5751002
Mike Clancy4,510Science & Technology ... if you want it, this is where you'll find it. These people are interesting and active. If you're in it, share it ... if you want into it, +1 it. It's that simple!2012-04-20 03:25:1149912626
Science on Google+2,105Psychology and Neuroscience PagesClick on the following link to view the pages in this circle: http://goo.gl/MwpSt. If you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/vOJoN). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.View underlying database: http://goo.gl/Yz8KRView most recent shared circles: http://goo.gl/nO7rB2012-04-14 14:19:0130428
Science on Google+1,707Science Pages- All disciplinesClick on the following link to view the pages in this circle: http://goo.gl/WCohT. If you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/vOJoN). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.View underlying database: http://goo.gl/Yz8KRView most recent shared circles: http://goo.gl/nO7rB2012-04-11 13:04:06810911
Mike Clancy3,675By far my largest (and favorite) circle, this is a great list of engaged science & technology lovers. As with my sci-fi circle, +1 this if you would like to be added to the circle, share it if you're already in it and want your own circles to grow.2012-04-05 16:33:35460101733
Science on Google+1,505Psychology/Neuroscience PagesClick on the following link to view the pages in this circle: http://goo.gl/MwpSt. If you have a science related degree, you are a science journalist, you are a K-12 science teacher, or you curate a science page, then add your profile/page to the database (http://goo.gl/vOJoN). Please note that you also have to circle +Science on Google+: A Public Database if you would like to be considered for shared circles.View underlying database: http://goo.gl/Yz8KRView most recent shared circles: http://goo.gl/nO7rB2012-04-04 01:14:30290417
Chris Robinson19,669Science Pages- Updated 3.15.12The pages in this circle cover many important areas/disciplines including: #Anthropology , #Astronomy , #Biology , #Biotechnology , #Botany , #Chemistry , #Climatology , #Ecology , #Geography , #Geology , #Mathematics , #Nanotechnology , #Neurology , #Neuroscience , #Psychology , #Physics , and #robotics . Help spread the love of Science by sharing this circle with your friends/circles.Do you want to add a Science page to the next shared circle? Mention the page on the original post.Pages that will be included in the next circle: +NIH +LA Robotics Club +MicrobiologyBytes +Eye-Com Research +Springer Plants _______________________________Musician and Band Public Database: http://goo.gl/EhCJaShared Circles and Helpful Google+ Links: http://goo.gl/i604C2012-03-15 12:05:16118111713
Chris Robinson19,669Psychology Pages- Updated 3.15.12This circle covers many areas of Psychology including: #ClinicalPsychology , #CognitiveBehavioralTherapy , #CognitivePsychology , #DevelopmentalPsychology , #EducationalPsychology , #Neurology , #NeuroMarketing , #Neuroscience , #Psychotherapy , #SocialPsychology , and there is even a page devoted to +Psychology Humour! Help spread the love of Psychology by sharing this circle with your friends!Do you want to add a Psychology page to the next shared circle? Mention the page on the original post.Pages to add to next shared circle: +NIH __________________________________Musician and Band Public Database: http://goo.gl/EhCJaShared Circles and Helpful Google+ Links: http://goo.gl/i604C2012-03-15 12:03:12495106
G+ Shared Circles Directory for Pages194The Science & Technology ~Pages-Only~ Circle! Add these groups and businesses to your circles with a click of a button. Each profile in this circle is a page which means that other pages can add them to circles too!If you'd like to be added to this circle, just leave a comment below.2012-03-13 19:21:241124110
Wilco Wings1,54203.03.02 Psychology, Psychiatry & MedsIf you're interested to be in this circle's next update, leave a comment. You can also suggest people for this circle.Well, let's try something new here...When you start at Google+, you get a couple of default circles, and when I think back, I had no clue what to do with it. I read a lot of tuts about circle management etc. Started over a few times (bad habit), but it didn’t really worked out for me.I tried to get a number of people interested in Google+ by demonstrating it on the screen. I noticed how confused they were.So I started over with my circle management again, now with a different approach. I took all my interests in my daily live, converted them into interest circles. When I demonstrate Google+ to people now, I don’t see those confused looks anymore, must done something right here.Most Google+ users keep there circle management for themselves (I noticed). I’m going to do the opposite here, I’m gonna share more than 40 interest circles, handpicked (except the Galaxy Nexus circle and the Chromebook circle, these are started by others shared circles).2012-02-28 22:11:3383221
Igbo Anyanwu1,792My Massive Science Circle.2012-02-27 09:14:56501014
Chris Robinson15,978Science Pages- Updated 2.13.12The pages in this circle cover many important areas/disciplines including: #Anthropology , #Astronomy , #Biology , #Biotechnology , #Botany , #Chemistry , #Climatology , #Ecology , #Geography , #Geology , #Mathematics , #Nanotechnology , #Neurology , #Neuroscience , #Psychology , and #Physics . Spread the love of Science by sharing this circle with your friends/circles.Pages that will be included in the next circle: +Ask A Biologist +HuffPost Science +Sleep Research +Oxford SciBar +Emily Lakdawalla, Planetary Society Blogger +CosmoQuest Do you want to add a Science page to the next shared circle? Mention the page on the original post: http://goo.gl/6BRLF._________________________________________________Science Circles and Helpful Google+ Links: http://goo.gl/i604C2012-02-13 16:01:3910691614
Chris Robinson14,511Science in a CircleA circle is a simple shape of Euclidean geometry consisting of those points in a plane that are a given distance from a given point, the centre. The distance between any of the points and the centre is called the radius. The word "circle" derives from the Greek, kirkos "a circle," from the base ker- which means to turn or bend. The origins of the words "circus" and "circuit" are closely related. The circle has been known since before the beginning of recorded history. Natural circles would have been observed, such as the Moon, Sun, and a short plant stalk blowing in the wind on sand, which forms a circle shape in the sand. The circle is the basis for the wheel, which, with related inventions such as gears, makes much of modern civilisation possible. In mathematics, the study of the circle has helped inspire the development of geometry, astronomy, and calculus. Excerpt taken from: http://goo.gl/P21YC.Here on Google+ circle has a different meaning. It's a powerful tool for categorizing profiles and pages. Circles can be beautiful and informative, especially when they're filled with science! I am sharing 50 pages that actively disseminate scientific material; however, it would be nice to build up this circle, as well as the scientific community more generally. Please comment on the original post (http://goo.gl/V1VyI) if you know of other high quality science pages on Google+. Feel free to share this circle with your friends, and don't forget to periodically check the comments in the original post (http://goo.gl/V1VyI) to see the recommended science pages.Science pages not included in circle: +Cancer Research UK, +Environmental Health News, +Research cc: +Allison Sekuler +Robby Bowles +ScienceSunday #sciencesunday2012-01-22 20:01:1450211124
G+ Business Pages Directory5,276Selection of +Google+ Your Business Pages from M-Z SHARED CIRCLEThis is a small selection of the many pages in the directory to check out. Pages included were done more in a general way and not specific ...in any way except for being in the 2nd half of the alphabet!A fun way to find pages you may not know about! #coolpages2012-01-08 20:17:30343261218
G+ Business Pages Directory3,402Psychology Pages Shared CircleI received a great interaction with +Chris Robinson today who has a major interest in the sciences and making circles related to All things ScienceMany thanks to him for helping +G+ Business Pages Directory make this circle!Feel free to suggest any other #psych and #science related Pages!#coolpages2011-12-07 22:40:4114349
Chris Robinson8,261General Science Circle with an emphasis on Psychology and Neuroscience Please comment below if you have found other Psychology/Neuroscience pages. Thanks!Here's the link to the OP (http://goo.gl/FpSeL), so you can check for additions.General Science Pages not included in shared circle+Cambridge Science Festival +Discover Magazine +New Scientist +ScienceBlog.com +ScienceDaily +SciFri +Science News Blog+ScienceSunday +Science of Tomorrow +Scientific AmericanPsychology and Neuroscience Pages not included in shared circle+Action Potential (neuro@nature) +All About Psychology +American Psychological Association +Brain Science Podcast +Cognando +Developmental Psychology News +NeuroDebian 2011-11-14 14:32:0417151514

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Top posts in the last 50 posts

Most comments: 8

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2014-10-15 22:02:32 (8 comments, 6 reshares, 17 +1s)Open 

Brain Surgery Through the Cheek

Full article at http://neurosciencenews.com/robotics-neurosurgery-hippocampus-1438.

For those most severely affected, treating epilepsy means drilling through the skull deep into the brain to destroy the small area where the seizures originate – invasive, dangerous and with a long recovery period.

Image: Patient mockup of surgical robot designed to treat epilepsy by entering the brain through the cheek. Credit Laboratory for the Design and Control of Energetic Systems / Vanderbilt.

#robotics   #neurosurgery   #neuroscience  

Most reshares: 30

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2014-10-22 22:01:47 (2 comments, 30 reshares, 52 +1s)Open 

Mathematical Model Shows How the Brain Remains Stable During Learning

Full article at http://neurosciencenews.com/odp-hebbian-plasticity-learning-1466.

Complex biochemical signals that coordinate fast and slow changes in neuronal networks keep the brain in balance during learning, according to an international team of scientists from the RIKEN Brain Science Institute in Japan, UC San Francisco (UCSF), and Columbia University in New York. 

The research is in Neuron. (full access paywall)

Research: “Modeling the Dynamic Interaction of Hebbian and Homeostatic Plasticity” by Taro Toyoizumi, Megumi Kaneko, Michael P. Stryker, and Kenneth D. Miller in Neuron. doi:10.1016/j.neuron.2014.09.036

Image: The theory and experimental findings showed that fast Hebbian and slow homeostatic plasticity work together during learning, but onlyafte... more »

Most plusones: 75

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2014-10-20 22:34:24 (2 comments, 17 reshares, 75 +1s)Open 

Study Suggests Mental Rest and Reflection Boost Learning

Full article at http://neurosciencenews.com/mental-rest-learning-memory-neuroscience-1458.

A new study, which may have implications for approaches to education, finds that brain mechanisms engaged when people allow their minds to rest and reflect on things they’ve learned before may boost later learning.

The research is in PNAS. (full access paywall)

Research: “Memory reactivation during rest supports upcoming learning of related content” by Margaret L. Schlichting and Alison R. Preston in PNAS. doi:10.1073/pnas.1404396111

Image: The patterns of brain activity recorded in this fMRI scanner revealed how mental rest and reflection on past learning activities can boost future learning. Credit Jeff Luci.

#neuroscience   #learning   #memory  

Latest 50 posts

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2014-10-28 21:01:25 (1 comments, 5 reshares, 18 +1s)Open 

Scientists Uncover Major Factor in Development of Huntington’s Disease

Full article at http://neurosciencenews.com/neurology-huntingtin-mtorc1-genetics-1483.

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a major contributor to Huntington’s disease, a devastating progressive neurological condition that produces involuntary movements, emotional disturbance and cognitive impairment.

The research is in Science Signaling. (full access paywall)

Research: "Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington’s disease" by William M. Pryor, Marta Biagioli, Neelam Shahani, Supriya Swarnkar, Wen-Chin Huang, Damon T. Page, Marcy E. MacDonald, and Srinivasa Subramaniam in Science Signaling. doi:10.1126/scisignal.2005633

Image: Depleting huntingtin reduces mTORC1activ... more »

Scientists Uncover Major Factor in Development of Huntington’s Disease

Full article at http://neurosciencenews.com/neurology-huntingtin-mtorc1-genetics-1483.

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a major contributor to Huntington’s disease, a devastating progressive neurological condition that produces involuntary movements, emotional disturbance and cognitive impairment.

The research is in Science Signaling. (full access paywall)

Research: "Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington’s disease" by William M. Pryor, Marta Biagioli, Neelam Shahani, Supriya Swarnkar, Wen-Chin Huang, Damon T. Page, Marcy E. MacDonald, and Srinivasa Subramaniam in Science Signaling. doi:10.1126/scisignal.2005633

Image: Depleting huntingtin reduces mTORC1 activity; an overexpression of huntingtin increases it. This image is for illustrative purposes only and shows the crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallographic purposes Credit Boghog.

#neurology   #huntingtonsdisease   #genetics  ___

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2014-10-28 20:31:17 (2 comments, 6 reshares, 27 +1s)Open 

Better Chemotherapy Through Targeted Delivery

Full article at http://neurosciencenews.com/brain-cancer-chemotherapy-microcapsules-1482.

New approach could kill tumor cells in the brain more effectively and avoid side effects.

The research is in PNAS. (full access paywall)

Research: “Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain” by Urvashi M. Upadhyay, Betty Tyler, Yoda Patta, Robert Wicks, Kevin Spencer, Alexander Scott, Byron Masi, Lee Hwang, Rachel Grossman, Michael Cima, Henry Brem, and Robert Langer in PNAS. doi:10.1073/pnas.1313420110

Image: Microcapsules that deliver chemotherapy directly to the brain could offer a better way to treat tumors. Credit Christine Daniloff/MIT.

#neurology   #cancer   #chemotherapy  

Better Chemotherapy Through Targeted Delivery

Full article at http://neurosciencenews.com/brain-cancer-chemotherapy-microcapsules-1482.

New approach could kill tumor cells in the brain more effectively and avoid side effects.

The research is in PNAS. (full access paywall)

Research: “Intracranial microcapsule chemotherapy delivery for the localized treatment of rodent metastatic breast adenocarcinoma in the brain” by Urvashi M. Upadhyay, Betty Tyler, Yoda Patta, Robert Wicks, Kevin Spencer, Alexander Scott, Byron Masi, Lee Hwang, Rachel Grossman, Michael Cima, Henry Brem, and Robert Langer in PNAS. doi:10.1073/pnas.1313420110

Image: Microcapsules that deliver chemotherapy directly to the brain could offer a better way to treat tumors. Credit Christine Daniloff/MIT.

#neurology   #cancer   #chemotherapy  ___

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2014-10-28 19:54:31 (0 comments, 3 reshares, 16 +1s)Open 

Pair Bonding Reinforced in the Brain

Full article at http://neurosciencenews.com/song-communication-neurobiology-mating-1481.

Zebra finches use their specialised song system for simple communication.

The research is in PLOS ONE. (full open access)

Research: “Zebra finch mates use their forebrain song system in unlearned call communication” by Andries Ter Maat, Lisa Trost, Hannes Sagunsky, Susanne Seltmann, and Manfred Gahr in PLOS ONE. doi:10.1371/journal.pone.0109334

Image: The song of the zebra finch seems to have evolved from a simple system for innate calls. Credit MPI f. Ornithology/ S. Seltmann.

#neuroscience   #behavior  

Pair Bonding Reinforced in the Brain

Full article at http://neurosciencenews.com/song-communication-neurobiology-mating-1481.

Zebra finches use their specialised song system for simple communication.

The research is in PLOS ONE. (full open access)

Research: “Zebra finch mates use their forebrain song system in unlearned call communication” by Andries Ter Maat, Lisa Trost, Hannes Sagunsky, Susanne Seltmann, and Manfred Gahr in PLOS ONE. doi:10.1371/journal.pone.0109334

Image: The song of the zebra finch seems to have evolved from a simple system for innate calls. Credit MPI f. Ornithology/ S. Seltmann.

#neuroscience   #behavior  ___

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2014-10-27 23:21:48 (5 comments, 21 reshares, 40 +1s)Open 

Ultrasound Guides Tongue to Pronounce ‘R’ Sounds

Full article at http://neurosciencenews.com/language-development-ultrasound-psychology-1480.

Using ultrasound technology to visualize the tongue’s shape and movement can help children with difficulty pronouncing “r” sounds, according to a small study by NYU’s Steinhardt School of Culture, Education, and Human Development and Montclair State University.

The research is in Journal of Speech, Language, and Hearing Research. (full access paywall)

Research: “Retroflex Versus Bunched in Treatment for Rhotic Misarticulation: Evidence From Ultrasound Biofeedback Intervention” by Tara McAllister Byun, Elaine R. Hitchcock, and Michelle T. Swartz in Journal of Speech, Language, and Hearing Research. doi:10.1044/2014_JSLHR-S-14-0034

Image: Using ultrasound technology to visualizethe tongue’s sh... more »

Ultrasound Guides Tongue to Pronounce ‘R’ Sounds

Full article at http://neurosciencenews.com/language-development-ultrasound-psychology-1480.

Using ultrasound technology to visualize the tongue’s shape and movement can help children with difficulty pronouncing “r” sounds, according to a small study by NYU’s Steinhardt School of Culture, Education, and Human Development and Montclair State University.

The research is in Journal of Speech, Language, and Hearing Research. (full access paywall)

Research: “Retroflex Versus Bunched in Treatment for Rhotic Misarticulation: Evidence From Ultrasound Biofeedback Intervention” by Tara McAllister Byun, Elaine R. Hitchcock, and Michelle T. Swartz in Journal of Speech, Language, and Hearing Research. doi:10.1044/2014_JSLHR-S-14-0034

Image: Using ultrasound technology to visualize the tongue’s shape and movement can help children with difficulty pronouncing “r” sounds, according to research led by NYU Steinhardt assistant professor Tara McAllister Byun. Credit NYU.

#neuroscience   #language   #psychology  ___

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2014-10-27 22:54:26 (1 comments, 15 reshares, 26 +1s)Open 

Synapses Always on the Starting Blocks

Full article at http://neurosciencenews.com/vesicle-fusion-synapses-neuroscience-1479.

Vesicles filled with neurotransmitters touch the cell membrane, thereby enabling their rapid-fire release.

The research is in Neuron. (full access paywall)

Research: “The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones” by Imig, C., Min, S.-W., Krinner, S., Arancillo, M., Rosenmund, C., Südhof, T.C., Rhee, J.-S., Brose, N. and Cooper, B.H in Neuron. doi:10.1016/j.neuron.2014.10.009

Image: Three-dimensional reconstruction of a synapse in the mouse brain. Readily releasable fusionable synaptic vesicles (blue, around 45 millionths of a millimetre in diameter) are docked at the cell membrane. Credit Benjamin H. Cooper.

#neuroscience   #synapse  

Synapses Always on the Starting Blocks

Full article at http://neurosciencenews.com/vesicle-fusion-synapses-neuroscience-1479.

Vesicles filled with neurotransmitters touch the cell membrane, thereby enabling their rapid-fire release.

The research is in Neuron. (full access paywall)

Research: “The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones” by Imig, C., Min, S.-W., Krinner, S., Arancillo, M., Rosenmund, C., Südhof, T.C., Rhee, J.-S., Brose, N. and Cooper, B.H in Neuron. doi:10.1016/j.neuron.2014.10.009

Image: Three-dimensional reconstruction of a synapse in the mouse brain. Readily releasable fusionable synaptic vesicles (blue, around 45 millionths of a millimetre in diameter) are docked at the cell membrane. Credit Benjamin H. Cooper.

#neuroscience   #synapse  ___

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2014-10-27 22:18:25 (0 comments, 4 reshares, 12 +1s)Open 

Study Gives New View on How Cells Control What Comes In and Out

Full article at http://neurosciencenews.com/ion-channel-disorders-neuroscience-1478.

Find could be central to treating channel-related diseases such as cardiac arrhythmias, epilepsy and Parkinson’s.

The research is in Cell. (full access paywall)

Research: “Apocalmodulin Itself Promotes Ion Channel Opening and Ca2+ Regulation” by Paul J. Adams, Manu Ben-Johny, Ivy E. Dick, Takanari Inoue, and David T. Yue in Cell. doi:10.1016/j.cell.2014.09.047

Image: The dynamic interplay of calcium-free calmodulin (white yang domain) and calcium-bound calmodulin (dark yin domain) controls the opening of ion channels, shown in the background. Credit Manu Ben-Johny and David Yue/Johns Hopkins Medicine.

#neuroscience   #parkinsons  

Study Gives New View on How Cells Control What Comes In and Out

Full article at http://neurosciencenews.com/ion-channel-disorders-neuroscience-1478.

Find could be central to treating channel-related diseases such as cardiac arrhythmias, epilepsy and Parkinson’s.

The research is in Cell. (full access paywall)

Research: “Apocalmodulin Itself Promotes Ion Channel Opening and Ca2+ Regulation” by Paul J. Adams, Manu Ben-Johny, Ivy E. Dick, Takanari Inoue, and David T. Yue in Cell. doi:10.1016/j.cell.2014.09.047

Image: The dynamic interplay of calcium-free calmodulin (white yang domain) and calcium-bound calmodulin (dark yin domain) controls the opening of ion channels, shown in the background. Credit Manu Ben-Johny and David Yue/Johns Hopkins Medicine.

#neuroscience   #parkinsons  ___

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2014-10-27 00:29:15 (0 comments, 10 reshares, 35 +1s)Open 

Activity in Dendrites is Critical in Memory Formation

Full article at http://neurosciencenews.com/neuroscience-dendrite-memory-formation-1477.

Study sheds light on why we might remember some things and not others.

The research is in Nature. (full access paywall)

Research:“Calcium transient prevalence across the dendritic arbour predicts place field properties” by Mark E. J. Sheffield and Daniel A. Dombeck in Nature. doi:10.1038/nature13871

Image: The research point to dendrites as a new potential target for therapeutics to combat memory deficits and debilitating diseases, such as Alzheimer’s disease (AD). This image is for illustrative purposes only. Credit geralt.

#neuroscience   #memory  

Activity in Dendrites is Critical in Memory Formation

Full article at http://neurosciencenews.com/neuroscience-dendrite-memory-formation-1477.

Study sheds light on why we might remember some things and not others.

The research is in Nature. (full access paywall)

Research:“Calcium transient prevalence across the dendritic arbour predicts place field properties” by Mark E. J. Sheffield and Daniel A. Dombeck in Nature. doi:10.1038/nature13871

Image: The research point to dendrites as a new potential target for therapeutics to combat memory deficits and debilitating diseases, such as Alzheimer’s disease (AD). This image is for illustrative purposes only. Credit geralt.

#neuroscience   #memory  ___

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2014-10-26 21:38:05 (0 comments, 5 reshares, 19 +1s)Open 

Real Time Readout of Neurochemical Activity

Full article at http://neurosciencenews.com/cnifers-neurochemical-detection-dopamine-1476.

Engineered cells reveal changes associated with learning, memory and reward.

The research is in Nature Methods. (full access paywall)

Research: “Cell-based reporters reveal in vivo dynamics of dopamine and norepinephrine release in murine cortex” by Arnaud Muller, Victory Joseph, Paul A Slesinger & David Kleinfeld in Nature Methods. doi:10.1038/nmeth.3151

Image: Pale green cells are CNiFERs implanted in mouse brain. Traces in white illustrate shifts in the timing of dopamine release with learning, a change the CNiFERs allowed researchers to track in real time. Credit Kleinfeld Lab, UC San Diego.

#neuroscience   #dopamine  

Real Time Readout of Neurochemical Activity

Full article at http://neurosciencenews.com/cnifers-neurochemical-detection-dopamine-1476.

Engineered cells reveal changes associated with learning, memory and reward.

The research is in Nature Methods. (full access paywall)

Research: “Cell-based reporters reveal in vivo dynamics of dopamine and norepinephrine release in murine cortex” by Arnaud Muller, Victory Joseph, Paul A Slesinger & David Kleinfeld in Nature Methods. doi:10.1038/nmeth.3151

Image: Pale green cells are CNiFERs implanted in mouse brain. Traces in white illustrate shifts in the timing of dopamine release with learning, a change the CNiFERs allowed researchers to track in real time. Credit Kleinfeld Lab, UC San Diego.

#neuroscience   #dopamine  ___

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2014-10-24 21:42:48 (1 comments, 15 reshares, 30 +1s)Open 

Navigation for Nerve Cells

Full article at http://neurosciencenews.com/flrt-neurodevelopment-pyramidal-cells-1475.

FLRT proteins direct precursors of pyramidal cells to their destination by attractant and repellent signals.

The research is in Neuron. (full open access)

Research: “FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development” by Elena Seiradake, Daniel del Toro, Daniel Nagel, Florian Cop, Ricarda Härtl, Tobias Ruff, Gönül Seyit-Bremer, Karl Harlos, Ellen Clare Border, Amparo Acker-Palmer, E.Yvonne Jones, and Rüdiger Klein in Neuron. doi:10.1016/j.neuron.2014.10.008 (http://dx.doi.org/10.1016/j.neuron.2014.10.008)

Image: Neurons with the Unc5-receptor send their axons in a cell culture in all directions. The processes avoid the parallel orientated stripes containing theFLRT3-p... more »

Navigation for Nerve Cells

Full article at http://neurosciencenews.com/flrt-neurodevelopment-pyramidal-cells-1475.

FLRT proteins direct precursors of pyramidal cells to their destination by attractant and repellent signals.

The research is in Neuron. (full open access)

Research: “FLRT structure: balancing repulsion and cell adhesion in cortical and vascular development” by Elena Seiradake, Daniel del Toro, Daniel Nagel, Florian Cop, Ricarda Härtl, Tobias Ruff, Gönül Seyit-Bremer, Karl Harlos, Ellen Clare Border, Amparo Acker-Palmer, E.Yvonne Jones, and Rüdiger Klein in Neuron. doi:10.1016/j.neuron.2014.10.008 (http://dx.doi.org/10.1016/j.neuron.2014.10.008)

Image: Neurons with the Unc5-receptor send their axons in a cell culture in all directions. The processes avoid the parallel orientated stripes containing the FLRT3-protein (red). Credit Seiradake et al, Neuron.

#neuroscience  ___

posted image

2014-10-24 21:06:07 (1 comments, 9 reshares, 29 +1s)Open 

Scientists Engineer Toxin Secreting Stem Cells to Treat Brain Tumors

Full article at http://neurosciencenews.com/stem-cells-glioblastoma-toxins-1474.

Proof-of-concept study highlights new therapeutic use of engineered human stem cells.

The research is in Stem Cells. (full access paywall)

Research: "Engineering toxin-resistant therapeutic stem cells to treat brain tumors" by Daniel W. Stuckey, Shawn D. Hingtgen, Nihal Karakas, Benjamin E. Rich and Khalid Shah in Stem Cells. doi:10.1002/stem.1874

Image: Cytotoxins are deadly to all cells, but since the late 1990s, researchers have been able to tag toxins in such a way that they only enter cancer cells with specific surface molecules; making it possible to get a toxin into a cancer cell without posing a risk to normal cells. Credit Harvard.

#neurology   #cancer... more »

Scientists Engineer Toxin Secreting Stem Cells to Treat Brain Tumors

Full article at http://neurosciencenews.com/stem-cells-glioblastoma-toxins-1474.

Proof-of-concept study highlights new therapeutic use of engineered human stem cells.

The research is in Stem Cells. (full access paywall)

Research: "Engineering toxin-resistant therapeutic stem cells to treat brain tumors" by Daniel W. Stuckey, Shawn D. Hingtgen, Nihal Karakas, Benjamin E. Rich and Khalid Shah in Stem Cells. doi:10.1002/stem.1874

Image: Cytotoxins are deadly to all cells, but since the late 1990s, researchers have been able to tag toxins in such a way that they only enter cancer cells with specific surface molecules; making it possible to get a toxin into a cancer cell without posing a risk to normal cells. Credit Harvard.

#neurology   #cancer   #genetics  ___

posted image

2014-10-24 20:21:00 (1 comments, 11 reshares, 32 +1s)Open 

Positive and Negative Memories Switched in Mouse Hippocampus Optogenetics Experiment

Full article at http://neurosciencenews.com/emotion-memory-neuroscience-bla-1473.

Neurons that encode whether a memory is positive or negative can be reprogrammed to switch the emotional association of the experience.

The research is in Nature. (full access paywall)

Research: “Bidirectional switch of the valence associated with a hippocampal contextual memory engram” by Roger L. Redondo, Joshua Kim, Autumn L. Arons, Steve Ramirez, Xu Liu and Susumu Tonegawa in Nature. doi:10.1038/nature13725

Image: A magnified image of a mouse brain showing memory cells (red) that can be turned ‘on’ and ‘off’ using light delivered by a fiber optic cable (black). Credit Susumu Tonegawa.

#neuroscience   #memory   #ptsd   #optogenetics  

Positive and Negative Memories Switched in Mouse Hippocampus Optogenetics Experiment

Full article at http://neurosciencenews.com/emotion-memory-neuroscience-bla-1473.

Neurons that encode whether a memory is positive or negative can be reprogrammed to switch the emotional association of the experience.

The research is in Nature. (full access paywall)

Research: “Bidirectional switch of the valence associated with a hippocampal contextual memory engram” by Roger L. Redondo, Joshua Kim, Autumn L. Arons, Steve Ramirez, Xu Liu and Susumu Tonegawa in Nature. doi:10.1038/nature13725

Image: A magnified image of a mouse brain showing memory cells (red) that can be turned ‘on’ and ‘off’ using light delivered by a fiber optic cable (black). Credit Susumu Tonegawa.

#neuroscience   #memory   #ptsd   #optogenetics  ___

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2014-10-23 22:42:36 (1 comments, 1 reshares, 27 +1s)Open 

Chemists Show That ALS Is a Protein Aggregation Disease

Full article at http://neurosciencenews.com/sod1-als-genetics-neurology-1472.

Using a technique that illuminates subtle changes in individual proteins, chemistry researchers at Cornell have uncovered new insight into the underlying causes of Amyotrophic Lateral Sclerosis (ALS).

The research is in PNAS and Biophysical Journal. (full access paywall)

Research: "Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes" by Brian R. Crane et al. in PNAS. doi:10.1073/pnas.1308531111

"Copper-Based Pulsed Dipolar ESR Spectroscopy as a Probe of Protein Conformation Linked to Disease States" by Brian R. Crane et al.in Biophysical Journal. doi:10.1016/j.bpj.2014.07.068

Image: For a long time, people have studied... more »

Chemists Show That ALS Is a Protein Aggregation Disease

Full article at http://neurosciencenews.com/sod1-als-genetics-neurology-1472.

Using a technique that illuminates subtle changes in individual proteins, chemistry researchers at Cornell have uncovered new insight into the underlying causes of Amyotrophic Lateral Sclerosis (ALS).

The research is in PNAS and Biophysical Journal. (full access paywall)

Research: "Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes" by Brian R. Crane et al. in PNAS. doi:10.1073/pnas.1308531111

"Copper-Based Pulsed Dipolar ESR Spectroscopy as a Probe of Protein Conformation Linked to Disease States" by Brian R. Crane et al.in Biophysical Journal. doi:10.1016/j.bpj.2014.07.068

Image: For a long time, people have studied mutations in SOD1 to try to understand ALS, but the properties of normal proteins and mutated ones were found to be very similar. By using ESR spectroscopy, the scientists for the first time have seen definitive differences. This image is for illustrative purposes only and show the structure of the SOD1 protein. Credit Emw.

#als   #neurology   #genetics  ___

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2014-10-23 21:03:27 (1 comments, 12 reshares, 38 +1s)Open 

Reminiscing Can Help Boost Mental Performance

Full article at http://neurosciencenews.com/psychology-mental-task-reminiscing-1471.

To solve a mental puzzle, the brain’s executive control network for externally focused, goal-oriented thinking must activate, while the network for internally directed thinking like daydreaming must be turned down to avoid interference – or so we thought.

The research is in Journal of Neuroscience. (full access paywall)

Research: "Goal-Congruent Default Network Activity Facilitates Cognitive Control" by R. Nathan Spreng, Elizabeth DuPre, Dhawal Selarka, Juliana Garcia1, Stefan Gojkovic, Judith Mildner, Wen-Ming Luh, and Gary R. Turner in Journal of Neuroscience. doi:10.1523/JNEUROSCI.2815-14.2014

Image: The researchers developed a new approach in which off-task processes such as reminiscingcan... more »

Reminiscing Can Help Boost Mental Performance

Full article at http://neurosciencenews.com/psychology-mental-task-reminiscing-1471.

To solve a mental puzzle, the brain’s executive control network for externally focused, goal-oriented thinking must activate, while the network for internally directed thinking like daydreaming must be turned down to avoid interference – or so we thought.

The research is in Journal of Neuroscience. (full access paywall)

Research: "Goal-Congruent Default Network Activity Facilitates Cognitive Control" by R. Nathan Spreng, Elizabeth DuPre, Dhawal Selarka, Juliana Garcia1, Stefan Gojkovic, Judith Mildner, Wen-Ming Luh, and Gary R. Turner in Journal of Neuroscience. doi:10.1523/JNEUROSCI.2815-14.2014

Image: The researchers developed a new approach in which off-task processes such as reminiscing can support rather than conflict with the aims of the experimental task. This image is for illustrative purposes only. Credit jarmoluk.

#psychology   #memory   #neuroscience  ___

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2014-10-23 20:10:16 (1 comments, 7 reshares, 24 +1s)Open 

Why People with Down Syndrome Invariably Develop Alzheimer’s Disease

Full article at http://neurosciencenews.com/snx27-beta-amyloid-down-syndrome-1470.

Findings have important implications for the development of treatments that can prevent damage in neuronal connectivity and brain function in Down syndrome and other neurodevelopmental and neurodegenerative conditions, including Alzheimer’s disease.

The research is in Cell Reports. (full open access)

Research: “Sorting Nexin 27 Regulates Aβ Production through Modulating γ-Secretase Activity” by Xin Wang, Timothy Huang, Yingjun Zhao, Qiuyang Zheng, Robert C. Thompson, Guojun Bu, Yun-wu Zhang, Wanjin Hong, and Huaxi Xu in Cell Reports. doi:10.1016/j.celrep.2014.09.037

Image: Amyloid plaques are found in the brains of people with Down syndrome and Alzheimer’s disease. CreditJuan Gartne... more »

Why People with Down Syndrome Invariably Develop Alzheimer’s Disease

Full article at http://neurosciencenews.com/snx27-beta-amyloid-down-syndrome-1470.

Findings have important implications for the development of treatments that can prevent damage in neuronal connectivity and brain function in Down syndrome and other neurodevelopmental and neurodegenerative conditions, including Alzheimer’s disease.

The research is in Cell Reports. (full open access)

Research: “Sorting Nexin 27 Regulates Aβ Production through Modulating γ-Secretase Activity” by Xin Wang, Timothy Huang, Yingjun Zhao, Qiuyang Zheng, Robert C. Thompson, Guojun Bu, Yun-wu Zhang, Wanjin Hong, and Huaxi Xu in Cell Reports. doi:10.1016/j.celrep.2014.09.037

Image: Amyloid plaques are found in the brains of people with Down syndrome and Alzheimer’s disease. Credit Juan Gartner.

#alzheimers   #neurology   #downsyndrome  ___

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2014-10-22 23:49:53 (2 comments, 12 reshares, 41 +1s)Open 

Human Skin Cells Reprogrammed Directly into Brain Cells

Full article at http://neurosciencenews.com/huntingtons-genetics-cell-reprogramming-1469.

Scientists have described a way to convert human skin cells directly into a specific type of brain cell affected by Huntington’s disease, an ultimately fatal neurodegenerative disorder. Unlike other techniques that turn one cell type into another, this new process does not pass through a stem cell phase, avoiding the production of multiple cell types, the study’s authors report.

The research is in Neuron. (full access paywall)

Research: “Generation of Human Striatal Neurons by MicroRNA-Dependent Direct Conversion of Fibroblasts” by Matheus B. Victor, Michelle Richner, Tracey O. Hermanstyne, Joseph L. Ransdell, Courtney Sobieski, Pan-Yue Deng, Vitaly A. Klyachko, Jeanne M. Nerbonne, and Andrew S. Yooin Neur... more »

Human Skin Cells Reprogrammed Directly into Brain Cells

Full article at http://neurosciencenews.com/huntingtons-genetics-cell-reprogramming-1469.

Scientists have described a way to convert human skin cells directly into a specific type of brain cell affected by Huntington’s disease, an ultimately fatal neurodegenerative disorder. Unlike other techniques that turn one cell type into another, this new process does not pass through a stem cell phase, avoiding the production of multiple cell types, the study’s authors report.

The research is in Neuron. (full access paywall)

Research: “Generation of Human Striatal Neurons by MicroRNA-Dependent Direct Conversion of Fibroblasts” by Matheus B. Victor, Michelle Richner, Tracey O. Hermanstyne, Joseph L. Ransdell, Courtney Sobieski, Pan-Yue Deng, Vitaly A. Klyachko, Jeanne M. Nerbonne, and Andrew S. Yoo in Neuron. doi:10.1016/j.neuron.2014.10.016

Image: Human skin cells (top) can be converted into medium spiny neurons (bottom) with exposure to the right combination of microRNAs and transcription factors, according to work by Andrew Yoo and his research team. Credit Yoo Lab.

#genetics   #neuroscience  ___

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2014-10-22 23:19:02 (0 comments, 7 reshares, 21 +1s)Open 

Neurons in a Forest of Signposts

Full article at http://neurosciencenews.com/proteases-axon-navigation-growth-neuroscience-1468.

Proteases help nerve cells to navigate.

The research is in Current Biology. (full access paywall)

Research: “EphA4 Receptor Shedding Regulates Spinal Motor Axon Guidance” by Graziana Gatto, Daniel Morales, Artur Kania, and Rüdiger Klein in Current Biology. doi:10.1016/j.cub.2014.08

Image: During development, nerve cells (shown in blue, green, violet and yellow) extend their axons to target leg muscles. If the EphA4 receptors of the growing nerve cells no longer encounter freely accessible ephrins, the axons of many nerve cells (violet) are no longer able to find their partner cells Credit Gatto/Max Planck Institute.

#neuroscience   #neurons  

Neurons in a Forest of Signposts

Full article at http://neurosciencenews.com/proteases-axon-navigation-growth-neuroscience-1468.

Proteases help nerve cells to navigate.

The research is in Current Biology. (full access paywall)

Research: “EphA4 Receptor Shedding Regulates Spinal Motor Axon Guidance” by Graziana Gatto, Daniel Morales, Artur Kania, and Rüdiger Klein in Current Biology. doi:10.1016/j.cub.2014.08

Image: During development, nerve cells (shown in blue, green, violet and yellow) extend their axons to target leg muscles. If the EphA4 receptors of the growing nerve cells no longer encounter freely accessible ephrins, the axons of many nerve cells (violet) are no longer able to find their partner cells Credit Gatto/Max Planck Institute.

#neuroscience   #neurons  ___

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2014-10-22 22:47:46 (5 comments, 12 reshares, 28 +1s)Open 

Light Alcohol Consumption During Later Life Associated With Better Episodic Memory

Full article at http://neurosciencenews.com/alcohol-aging-episodic-memory-1467.

Researchers from the University of Texas Medical Branch at Galveston, University of Kentucky, and University of Maryland found that for people 60 and older who do not have dementia, light alcohol consumption during late life is associated with higher episodic memory — the ability to recall memories of events.

The research is in American Journal of Alzheimer’s Disease and Other Dementias. (full access paywall)

Research: "Effects of Alcohol Consumption on Cognition and Regional Brain Volumes Among Older Adults" by Brian Downer, PhD, Yang Jiang, PhD, Faika Zanjani, PhD and David Fardo, PhD in American Journal of Alzheimer's Disease and Other Dementias.doi... more »

Light Alcohol Consumption During Later Life Associated With Better Episodic Memory

Full article at http://neurosciencenews.com/alcohol-aging-episodic-memory-1467.

Researchers from the University of Texas Medical Branch at Galveston, University of Kentucky, and University of Maryland found that for people 60 and older who do not have dementia, light alcohol consumption during late life is associated with higher episodic memory — the ability to recall memories of events.

The research is in American Journal of Alzheimer’s Disease and Other Dementias. (full access paywall)

Research: "Effects of Alcohol Consumption on Cognition and Regional Brain Volumes Among Older Adults" by Brian Downer, PhD, Yang Jiang, PhD, Faika Zanjani, PhD and David Fardo, PhD in American Journal of Alzheimer's Disease and Other Dementias. doi:10.1177/1533317514549411

Image: Researchers found that light and moderate alcohol consumption in older people is associated with higher episodic memory and is linked with larger hippocampal brain volume. This image is for illustrative purposes only. Credit rudolf_langer.

#neuroscience   #aging   #memory  ___

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2014-10-22 22:01:47 (2 comments, 30 reshares, 52 +1s)Open 

Mathematical Model Shows How the Brain Remains Stable During Learning

Full article at http://neurosciencenews.com/odp-hebbian-plasticity-learning-1466.

Complex biochemical signals that coordinate fast and slow changes in neuronal networks keep the brain in balance during learning, according to an international team of scientists from the RIKEN Brain Science Institute in Japan, UC San Francisco (UCSF), and Columbia University in New York. 

The research is in Neuron. (full access paywall)

Research: “Modeling the Dynamic Interaction of Hebbian and Homeostatic Plasticity” by Taro Toyoizumi, Megumi Kaneko, Michael P. Stryker, and Kenneth D. Miller in Neuron. doi:10.1016/j.neuron.2014.09.036

Image: The theory and experimental findings showed that fast Hebbian and slow homeostatic plasticity work together during learning, but onlyafte... more »

Mathematical Model Shows How the Brain Remains Stable During Learning

Full article at http://neurosciencenews.com/odp-hebbian-plasticity-learning-1466.

Complex biochemical signals that coordinate fast and slow changes in neuronal networks keep the brain in balance during learning, according to an international team of scientists from the RIKEN Brain Science Institute in Japan, UC San Francisco (UCSF), and Columbia University in New York. 

The research is in Neuron. (full access paywall)

Research: “Modeling the Dynamic Interaction of Hebbian and Homeostatic Plasticity” by Taro Toyoizumi, Megumi Kaneko, Michael P. Stryker, and Kenneth D. Miller in Neuron. doi:10.1016/j.neuron.2014.09.036

Image: The theory and experimental findings showed that fast Hebbian and slow homeostatic plasticity work together during learning, but only after each has independently assured stability on its own timescale. This image is for illustrative purposes only. Credit Nicolas P. Rougier.

#neuroscience   #mathematics   #learning  ___

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2014-10-22 21:23:00 (1 comments, 4 reshares, 15 +1s)Open 

New ALS Associated Gene Identified Using Innovative Strategy

Full article at http://neurosciencenews.com/tuba4a-familial-als-genetics-1465.

Using an innovative exome sequencing strategy, a team of international scientists led by John Landers, PhD, at the University of Massachusetts Medical School has shown that TUBA4A, the gene encoding the Tubulin Alpha 4A protein, is associated with familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder also known as Lou Gehrig’s Disease. 

The research is in Neuron. (full access paywall)

Research: “Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS” by John E. Landers et al. in Neuron. doi:10.1016/j.neuron.2014.09.027

Image: ALS is a progressive, neurodegenerative disorder affecting the motor neurons in the central nervous system.As mot... more »

New ALS Associated Gene Identified Using Innovative Strategy

Full article at http://neurosciencenews.com/tuba4a-familial-als-genetics-1465.

Using an innovative exome sequencing strategy, a team of international scientists led by John Landers, PhD, at the University of Massachusetts Medical School has shown that TUBA4A, the gene encoding the Tubulin Alpha 4A protein, is associated with familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder also known as Lou Gehrig’s Disease. 

The research is in Neuron. (full access paywall)

Research: “Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS” by John E. Landers et al. in Neuron. doi:10.1016/j.neuron.2014.09.027

Image: ALS is a progressive, neurodegenerative disorder affecting the motor neurons in the central nervous system. As motor neurons die, the brain’s ability to send signals to the body’s muscles is compromised. This leads to loss of voluntary muscle movement, paralysis and eventually respiratory failure. This image is adapted from the YouTube video associated with this article. Credit cellvideoabstracts.

#als   #neurology   #genetics  ___

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2014-10-22 20:45:31 (1 comments, 10 reshares, 19 +1s)Open 

Gait and Dementia Link Confirmed

Full article at http://neurosciencenews.com/gait-parkinsons-cognitive-function-1464.

Researchers at Newcastle University have found a definitive link between gait – the way someone walks – and early changes in cognitive function in people with Parkinson’s disease.

The research is in Frontiers in Aging Neuroscience. (full open access)

Research: “Cognition and Gait Show a Selective Pattern of Association Dominated by Phenotype in Incident Parkinson’s Disease” by Sue Lord, Brook Galna, Shirley Coleman, Alison Yarnall, David Burn and Lynn Rochester in Frontiers in Aging Neuroscience. doi:10.3389/fnagi.2014.00249

Image: Researchers say gait could be used as an early warning sign to help predict the cognitive decline associated with Parkinson’s disease. This image is for illustrative purposesonly and show... more »

Gait and Dementia Link Confirmed

Full article at http://neurosciencenews.com/gait-parkinsons-cognitive-function-1464.

Researchers at Newcastle University have found a definitive link between gait – the way someone walks – and early changes in cognitive function in people with Parkinson’s disease.

The research is in Frontiers in Aging Neuroscience. (full open access)

Research: “Cognition and Gait Show a Selective Pattern of Association Dominated by Phenotype in Incident Parkinson’s Disease” by Sue Lord, Brook Galna, Shirley Coleman, Alison Yarnall, David Burn and Lynn Rochester in Frontiers in Aging Neuroscience. doi:10.3389/fnagi.2014.00249

Image: Researchers say gait could be used as an early warning sign to help predict the cognitive decline associated with Parkinson’s disease. This image is for illustrative purposes only and shows a Parkinson’s patient in a flexed walking posture. Credit Albert Londe (1892).

#neurology   #parkinsons   #dementia  ___

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2014-10-21 21:30:34 (0 comments, 8 reshares, 24 +1s)Open 

Reading a Biological Clock in the Dark

Full article at http://neurosciencenews.com/circadian-clock-metabolic-disease-1463.

Proper coordination between our gut bacteria and our biological clocks may be crucial for preventing obesity and glucose intolerance.

The research is in Cell. (full open access)

Research: "Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis" by Christoph A. Thaiss, David Zeevi, Maayan Levy, Gili Zilberman-Schapira, Jotham Suez, Anouk C. Tengeler, Lior Abramson, Meirav N. Katz, Tal Korem, Niv Zmora, Yael Kuperman, Inbal Biton, Shlomit Gilad, Alon Harmelin, Hagit Shapiro, Zamir Halpern, Eran Segal, and Eran Elinav in Cell. doi:10.1016/j.cell.2014.09.048

Image: Researchers report our biological clock work in tandem with the populations of bacteria residing in our... more »

Reading a Biological Clock in the Dark

Full article at http://neurosciencenews.com/circadian-clock-metabolic-disease-1463.

Proper coordination between our gut bacteria and our biological clocks may be crucial for preventing obesity and glucose intolerance.

The research is in Cell. (full open access)

Research: "Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis" by Christoph A. Thaiss, David Zeevi, Maayan Levy, Gili Zilberman-Schapira, Jotham Suez, Anouk C. Tengeler, Lior Abramson, Meirav N. Katz, Tal Korem, Niv Zmora, Yael Kuperman, Inbal Biton, Shlomit Gilad, Alon Harmelin, Hagit Shapiro, Zamir Halpern, Eran Segal, and Eran Elinav in Cell. doi:10.1016/j.cell.2014.09.048

Image: Researchers report our biological clock work in tandem with the populations of bacteria residing in our intestines, and that these microorganisms vary their activities over the course of the day. Credit Weizmann Institute of Science.

#neuroscience   #circadianrhythm   #metabolism  ___

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2014-10-21 20:39:45 (0 comments, 8 reshares, 30 +1s)Open 

Immune Proteins Moonlight to Regulate Brain Cell Connections

Full article at http://neurosciencenews.com/mhci-synapse-insulin-neuroscience-1462.

When it comes to the brain, "more is better" seems like an obvious assumption. But in the case of synapses, which are the connections between brain cells, too many or too few can both disrupt brain function.

The research is in Journal of Neuroscience. (full access paywall)

Research: "MHC Class I Limits Hippocampal Synapse Density by Inhibiting Neuronal Insulin Receptor Signaling" by Tracy J. Dixon-Salazar, Lawrence Fourgeaud, Carolyn M. Tyler, Julianna R. Poole, Joseph J. Park, and Lisa M. Boulanger in Journal of Neuroscience. doi:10.1523/JNEUROSCI.4642-12.2014

Image: Pictured is a mouse hippocampal neuron studded with thousands of synaptic connections (yellow). The... more »

Immune Proteins Moonlight to Regulate Brain Cell Connections

Full article at http://neurosciencenews.com/mhci-synapse-insulin-neuroscience-1462.

When it comes to the brain, "more is better" seems like an obvious assumption. But in the case of synapses, which are the connections between brain cells, too many or too few can both disrupt brain function.

The research is in Journal of Neuroscience. (full access paywall)

Research: "MHC Class I Limits Hippocampal Synapse Density by Inhibiting Neuronal Insulin Receptor Signaling" by Tracy J. Dixon-Salazar, Lawrence Fourgeaud, Carolyn M. Tyler, Julianna R. Poole, Joseph J. Park, and Lisa M. Boulanger in Journal of Neuroscience. doi:10.1523/JNEUROSCI.4642-12.2014

Image: Pictured is a mouse hippocampal neuron studded with thousands of synaptic connections (yellow). The number and location of synapses -- not too many or too few -- is critical to healthy brain function. The researchers found that MHCI proteins, known for their role in the immune system, also are one of the only known factors that ensure synapse density is not too high. The protein does so by inhibiting insulin receptors, which promote synapse formation. Credit Lisa Boulanger.

#neuroscience   #synapse   #electrophysiology  ___

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2014-10-21 00:50:26 (2 comments, 15 reshares, 37 +1s)Open 

Researchers Untangle the Biological Effects of Blue Light

Full article at http://neurosciencenews.com/neuroscience-melanopsin-blue-light-1461.

A tug-of-war is revealed in the response of the eye to blue light, with implications for the study of light sensitivity and seasonal depression.

The research is in PNAS. (full open access)

Research: “Opponent melanopsin and S-cone signals in the human pupillary light response” by Manuel Spitschan, Sandeep Jain, David H. Brainard, and Geoffrey K. Aguirre in PNAS. doi:10.1073/pnas.1400942111

Image: Drs. Aguirre and Brainard and graduate student Spitschan found that melanopsin, a protein and short wave-sensitive S-cones, both in the retina have opposite effects and compete for control of the pupil in response to blue light. Credit University of Pennsylvania.

#neuroscience  #opt... more »

Researchers Untangle the Biological Effects of Blue Light

Full article at http://neurosciencenews.com/neuroscience-melanopsin-blue-light-1461.

A tug-of-war is revealed in the response of the eye to blue light, with implications for the study of light sensitivity and seasonal depression.

The research is in PNAS. (full open access)

Research: “Opponent melanopsin and S-cone signals in the human pupillary light response” by Manuel Spitschan, Sandeep Jain, David H. Brainard, and Geoffrey K. Aguirre in PNAS. doi:10.1073/pnas.1400942111

Image: Drs. Aguirre and Brainard and graduate student Spitschan found that melanopsin, a protein and short wave-sensitive S-cones, both in the retina have opposite effects and compete for control of the pupil in response to blue light. Credit University of Pennsylvania.

#neuroscience   #optogenetics  ___

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2014-10-21 00:18:03 (0 comments, 4 reshares, 21 +1s)Open 

Scientists Restore Hearing in Noise Deafened Mice

Full article at http://neurosciencenews.com/nt3-noise-deafness-genetics-hearing-restored-1460.

Scientists have restored the hearing of mice partly deafened by noise, using advanced tools to boost the production of a key protein in their ears.

The research is in eLife. (full open access)

Research: “Neurotrophin-3 regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma” by Guoqiang Wan, Maria E Gómez-Casati, Angelica R Gigliello, Charles Liberman, and Gabriel Corfas in eLife.  doi:10.7554/eLife.03564

Image: This microscope image of tissue from deep inside a normal mouse ear shows how ribbon synapses (red) form the connections between the hair cells of the inner ear (blue) and the tips of nerve cells (green) that connect to the brain.Credi... more »

Scientists Restore Hearing in Noise Deafened Mice

Full article at http://neurosciencenews.com/nt3-noise-deafness-genetics-hearing-restored-1460.

Scientists have restored the hearing of mice partly deafened by noise, using advanced tools to boost the production of a key protein in their ears.

The research is in eLife. (full open access)

Research: “Neurotrophin-3 regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma” by Guoqiang Wan, Maria E Gómez-Casati, Angelica R Gigliello, Charles Liberman, and Gabriel Corfas in eLife.  doi:10.7554/eLife.03564

Image: This microscope image of tissue from deep inside a normal mouse ear shows how ribbon synapses (red) form the connections between the hair cells of the inner ear (blue) and the tips of nerve cells (green) that connect to the brain. Credit Corfas lab/University of Michigan.

#neurology   #hearingloss   #genetics  ___

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2014-10-20 23:11:11 (0 comments, 8 reshares, 26 +1s)Open 

Tarantula Toxin is Used to Report on Electrical Activity in Live Cells

Full article at http://neurosciencenews.com/electrohoysiology-tarantula-toxin-ion-channel-1459.

Crucial experiments to develop a novel probe of cellular electrical activity were conducted in the Neurobiology course at the Marine Biological Laboratory (MBL) in 2013. Today, that optical probe, which combines a tarantula toxin with a fluorescent compound, is introduced in a paper in the Proceedings of the National Academy of Sciences.

The research is in PNAS. (full access paywall)

Research: “Chemoselective tarantula toxins report voltage activation of wild-type ion channels in live cells” by Drew C. Tilley, Kenneth S. Eum, Sebastian Fletcher-Taylor, Daniel C. Austin, Christophe Dupré, Lilian A. Patrón, Rita L. Garcia, Kit Lam, Vladimir Yarov-Yarovoy, Bruce E. Cohen, and Jon T.Sack ... more »

Tarantula Toxin is Used to Report on Electrical Activity in Live Cells

Full article at http://neurosciencenews.com/electrohoysiology-tarantula-toxin-ion-channel-1459.

Crucial experiments to develop a novel probe of cellular electrical activity were conducted in the Neurobiology course at the Marine Biological Laboratory (MBL) in 2013. Today, that optical probe, which combines a tarantula toxin with a fluorescent compound, is introduced in a paper in the Proceedings of the National Academy of Sciences.

The research is in PNAS. (full access paywall)

Research: “Chemoselective tarantula toxins report voltage activation of wild-type ion channels in live cells” by Drew C. Tilley, Kenneth S. Eum, Sebastian Fletcher-Taylor, Daniel C. Austin, Christophe Dupré, Lilian A. Patrón, Rita L. Garcia, Kit Lam, Vladimir Yarov-Yarovoy, Bruce E. Cohen, and Jon T. Sack in PNAS. doi:10.1073/pnas.1406876111

Image: The probe takes advantage of the potent ability of tarantula toxin to bind to electrically active cells, such as neurons, while the cells are in a resting state. The image is for illustrative purposes only. Credit WikiImages.

#neuroscience   #electrophysiology  ___

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2014-10-20 22:34:24 (2 comments, 17 reshares, 75 +1s)Open 

Study Suggests Mental Rest and Reflection Boost Learning

Full article at http://neurosciencenews.com/mental-rest-learning-memory-neuroscience-1458.

A new study, which may have implications for approaches to education, finds that brain mechanisms engaged when people allow their minds to rest and reflect on things they’ve learned before may boost later learning.

The research is in PNAS. (full access paywall)

Research: “Memory reactivation during rest supports upcoming learning of related content” by Margaret L. Schlichting and Alison R. Preston in PNAS. doi:10.1073/pnas.1404396111

Image: The patterns of brain activity recorded in this fMRI scanner revealed how mental rest and reflection on past learning activities can boost future learning. Credit Jeff Luci.

#neuroscience   #learning   #memory  

Study Suggests Mental Rest and Reflection Boost Learning

Full article at http://neurosciencenews.com/mental-rest-learning-memory-neuroscience-1458.

A new study, which may have implications for approaches to education, finds that brain mechanisms engaged when people allow their minds to rest and reflect on things they’ve learned before may boost later learning.

The research is in PNAS. (full access paywall)

Research: “Memory reactivation during rest supports upcoming learning of related content” by Margaret L. Schlichting and Alison R. Preston in PNAS. doi:10.1073/pnas.1404396111

Image: The patterns of brain activity recorded in this fMRI scanner revealed how mental rest and reflection on past learning activities can boost future learning. Credit Jeff Luci.

#neuroscience   #learning   #memory  ___

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2014-10-20 22:06:35 (1 comments, 8 reshares, 16 +1s)Open 

Why Your Brain Makes You Reach for Junk Food

Full article at http://neurosciencenews.com/neurobiology-caloric-content-cravings-1457.

New study examines link between brain cortex and food buying habits.

The research is in Psychological Science. (full access paywall)

Research: “Behavioral and Neural Valuation of Foods Is Driven by Implicit Knowledge of Caloric Content” by Deborah W. Tang, Lesley K. Fellows, and Alain Dagher in Psychological Science. doi:10.1177/0956797614552081

Image: Decisions about food consumption and caloric density are linked to a part of the brain called the ventromedial prefrontal cortex, an area that encodes the value of stimuli and predicts immediate consumption. This image is for illustrative purposes only. Credit NeuroscienceNews.com.

#neuroscience   #psychology  

Why Your Brain Makes You Reach for Junk Food

Full article at http://neurosciencenews.com/neurobiology-caloric-content-cravings-1457.

New study examines link between brain cortex and food buying habits.

The research is in Psychological Science. (full access paywall)

Research: “Behavioral and Neural Valuation of Foods Is Driven by Implicit Knowledge of Caloric Content” by Deborah W. Tang, Lesley K. Fellows, and Alain Dagher in Psychological Science. doi:10.1177/0956797614552081

Image: Decisions about food consumption and caloric density are linked to a part of the brain called the ventromedial prefrontal cortex, an area that encodes the value of stimuli and predicts immediate consumption. This image is for illustrative purposes only. Credit NeuroscienceNews.com.

#neuroscience   #psychology  ___

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2014-10-20 21:20:53 (1 comments, 6 reshares, 16 +1s)Open 

Rapid Agent Restores Pleasure Seeking Ahead of Other Antidepressant Action

Full article at http://neurosciencenews.com/ketamine-bipolar-disorder-psychiatry-1456.

A drug being studied as a fast-acting mood-lifter restored pleasure-seeking behavior independent of — and ahead of — its other antidepressant effects, in a National Institutes of Health trial. Within 40 minutes after a single infusion of ketamine, treatment-resistant depressed bipolar disorder patients experienced a reversal of a key symptom — loss of interest in pleasurable activities — which lasted up to 14 days. Brain scans traced the agent’s action to boosted activity in areas at the front and deep in the right hemisphere of the brain.

The research is in Translational Psychiatry. (full open access)

Research: “Anti-anhedonic effect of ketamine and its neural correlates intreatment-r... more »

Rapid Agent Restores Pleasure Seeking Ahead of Other Antidepressant Action

Full article at http://neurosciencenews.com/ketamine-bipolar-disorder-psychiatry-1456.

A drug being studied as a fast-acting mood-lifter restored pleasure-seeking behavior independent of — and ahead of — its other antidepressant effects, in a National Institutes of Health trial. Within 40 minutes after a single infusion of ketamine, treatment-resistant depressed bipolar disorder patients experienced a reversal of a key symptom — loss of interest in pleasurable activities — which lasted up to 14 days. Brain scans traced the agent’s action to boosted activity in areas at the front and deep in the right hemisphere of the brain.

The research is in Translational Psychiatry. (full open access)

Research: “Anti-anhedonic effect of ketamine and its neural correlates in treatment-resistant bipolar depression” by N Lally, A C Nugent, D A Luckenbaugh, R Ameli, J P Roiser and C A Zarate in Translational Psychiatry. doi:10.1038/tp.2014.105

Image: PET scans revealed that ketamine rapidly restored bipolar depressed patients’ ability to anticipate pleasurable experiences by boosting activity in the dorsal anterior cingulate cortex (yellow) and related circuitry. Picture shows PET scan data superimposed on anatomical MRI image. Credit NIH.

#psychology   #bipolar   #psychiatry  ___

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2014-10-20 20:37:21 (0 comments, 7 reshares, 19 +1s)Open 

Graphene Microelectrodes are Powerful Tools for Studying Epilepsy and Other Brain Disorders

Full article at http://neurosciencenews.com/graphene-electrode-electrophysiology-epilepsy-1455.

Researchers from the Perelman School of Medicine and School of Engineering at the University of Pennsylvania and The Children’s Hospital of Philadelphia have used graphene — a two-dimensional form of carbon only one atom thick — to fabricate a new type of microelectrode that solves a major problem for investigators looking to understand the intricate circuitry of the brain.

The research is in Nature Communications. (full access paywall)

Research: “Transparent and flexible low noise graphene electrodes for simultaneous electrophysiology and neuroimaging” by Duygu Kuzum, Hajime Takano, Euijae Shim, Jason C. Reed, Halvor Juul, Andrew G. Richardson, Julius deVries, Ha... more »

Graphene Microelectrodes are Powerful Tools for Studying Epilepsy and Other Brain Disorders

Full article at http://neurosciencenews.com/graphene-electrode-electrophysiology-epilepsy-1455.

Researchers from the Perelman School of Medicine and School of Engineering at the University of Pennsylvania and The Children’s Hospital of Philadelphia have used graphene — a two-dimensional form of carbon only one atom thick — to fabricate a new type of microelectrode that solves a major problem for investigators looking to understand the intricate circuitry of the brain.

The research is in Nature Communications. (full access paywall)

Research: “Transparent and flexible low noise graphene electrodes for simultaneous electrophysiology and neuroimaging” by Duygu Kuzum, Hajime Takano, Euijae Shim, Jason C. Reed, Halvor Juul, Andrew G. Richardson, Julius de Vries, Hank Bink, Marc A. Dichter, Timothy H. Lucas, Douglas A. Coulter, Ertugrul Cubukcu and Brian Litt in Nature Communications. doi:10.1038/ncomms6259

Image: Calcium imaging of neurons in a rat hippocampal slice through transparent graphene electrode. Black square at the center is transparent graphene electrode and neurons are shown in green. Yellow traces shows a representative example of electrophysiological recordings with graphene electrode. Credit Hajime Takano and Duygu Kuzum.

#neuroscience   #epilepsy   #technology  ___

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2014-10-17 23:32:36 (0 comments, 7 reshares, 32 +1s)Open 

Research Could Help Improve Bladder Function Among People with Spinal Cord Injuries

Full article at http://neurosciencenews.com/bladder-control-spinal-injury-neurology-1454.

Study addresses a critical health problem for those who are paralyzed.

The research is in PLOS ONE. (full open access)

Research: “Initiation of Bladder Voiding with Epidural Stimulation in Paralyzed, Step Trained Rats” by Parag N. Gad, Roland R. Roy, Hui Zhong, Daniel C. Lu, Yury P. Gerasimenko, and V. Reggie Edgerton in PLOS ONE. doi:10.1371/journal.pone.0108184

Image: In that study, researchers used a stimulator to deliver a continuous electrical current to the participants’ lower spinal cords, mimicking signals the brain normally transmits to initiate movement. This image is for illustrative purposes only. Credit BruceBlaus.

#neurology  #paral... more »

Research Could Help Improve Bladder Function Among People with Spinal Cord Injuries

Full article at http://neurosciencenews.com/bladder-control-spinal-injury-neurology-1454.

Study addresses a critical health problem for those who are paralyzed.

The research is in PLOS ONE. (full open access)

Research: “Initiation of Bladder Voiding with Epidural Stimulation in Paralyzed, Step Trained Rats” by Parag N. Gad, Roland R. Roy, Hui Zhong, Daniel C. Lu, Yury P. Gerasimenko, and V. Reggie Edgerton in PLOS ONE. doi:10.1371/journal.pone.0108184

Image: In that study, researchers used a stimulator to deliver a continuous electrical current to the participants’ lower spinal cords, mimicking signals the brain normally transmits to initiate movement. This image is for illustrative purposes only. Credit BruceBlaus.

#neurology   #paralysis   #spinalcordinjury  ___

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2014-10-17 22:52:46 (1 comments, 9 reshares, 32 +1s)Open 

YouTube as Peer Support for People with Severe Mental Illness

Full article at http://neurosciencenews.com/psychology-mental-health-peer-support-youtube-1452.

People with severe mental illness such as schizophrenia, schizoaffective disorder or bipolar disorder use a popular social media website like YouTube to provide and receive naturally occurring peer support, Dartmouth researchers report.

The research is in PLOS ONE. (full open access)

Research: "Naturally Occurring Peer Support through Social Media: The Experiences of Individuals with Severe Mental Illness Using YouTube" by John A. Naslund, Stuart W. Grande, Kelly A. Aschbrenner, and Glyn Elwyn in PLOS ONE. doi:10.1371/journal.pone.0110171

Image: Researchers found that people with severe mental illness used YouTube to feel less alone and to find hope, to support and to... more »

YouTube as Peer Support for People with Severe Mental Illness

Full article at http://neurosciencenews.com/psychology-mental-health-peer-support-youtube-1452.

People with severe mental illness such as schizophrenia, schizoaffective disorder or bipolar disorder use a popular social media website like YouTube to provide and receive naturally occurring peer support, Dartmouth researchers report.

The research is in PLOS ONE. (full open access)

Research: "Naturally Occurring Peer Support through Social Media: The Experiences of Individuals with Severe Mental Illness Using YouTube" by John A. Naslund, Stuart W. Grande, Kelly A. Aschbrenner, and Glyn Elwyn in PLOS ONE. doi:10.1371/journal.pone.0110171

Image: Researchers found that people with severe mental illness used YouTube to feel less alone and to find hope, to support and to defend each other, and to share personal stories and strategies for coping with day-to-day challenges. Credit Dartmouth University.

#psychology   #psychiatry   #mentalhealth  ___

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2014-10-17 21:57:54 (1 comments, 20 reshares, 43 +1s)Open 

How the Brain Leads Us to Believe We Have Sharp Vision

Full article at http://neurosciencenews.com/visual-perception-sharper-images-neuroscience-1451.

We assume that we can see the world around us in sharp detail. In fact, our eyes can only process a fraction of our surroundings precisely. In a series of experiments, psychologists at Bielefeld University have been investigating how the brain fools us into believing that we see in sharp detail.

The research is in Journal of Experimental Psychology: General. (full access paywall)

Research: “Predicting object features across saccades: Evidence from object recognition and visual search” by Arvid Herwig and Werner X. Schneider in Journal of Experimental Psychology: General. doi:10.1037/a0036781

Image: The thumbnail at the end of an outstretched arm: This is the area that the eyeact... more »

How the Brain Leads Us to Believe We Have Sharp Vision

Full article at http://neurosciencenews.com/visual-perception-sharper-images-neuroscience-1451.

We assume that we can see the world around us in sharp detail. In fact, our eyes can only process a fraction of our surroundings precisely. In a series of experiments, psychologists at Bielefeld University have been investigating how the brain fools us into believing that we see in sharp detail.

The research is in Journal of Experimental Psychology: General. (full access paywall)

Research: “Predicting object features across saccades: Evidence from object recognition and visual search” by Arvid Herwig and Werner X. Schneider in Journal of Experimental Psychology: General. doi:10.1037/a0036781

Image: The thumbnail at the end of an outstretched arm: This is the area that the eye actually can see in sharp detail. Researchers have investigated why the rest of the world also appears to be uniformly detailed. Credit Bielefeld University.

#neuroscience   #vision   #perception  ___

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2014-10-17 21:27:53 (2 comments, 8 reshares, 23 +1s)Open 

Study Finds Action Video Games May Bolster Sensorimotor Skills

Full article at http://neurosciencenews.com/gaming-sensorimotor-skills-neuroscience-1450.

A study led by University of Toronto psychology researchers has found that people who play action video games such as Call of Duty or Assassin’s Creed seem to learn a new sensorimotor skill more quickly than non-gamers do.

The research is in Human Movement Science. (full access paywall)

Research: “The effect of action video game playing on sensorimotor learning: Evidence from a movement tracking task” by Gozli DG, Bavelier D, and Pratt J in Human Movement Science. doi:10.1016/j.humov.2014.09.004

Image: Researchers wanted to test whether the superior performance of gamers was as a result of learning rather than having better sensorimotor control. This image is for illustrativepurpo... more »

Study Finds Action Video Games May Bolster Sensorimotor Skills

Full article at http://neurosciencenews.com/gaming-sensorimotor-skills-neuroscience-1450.

A study led by University of Toronto psychology researchers has found that people who play action video games such as Call of Duty or Assassin’s Creed seem to learn a new sensorimotor skill more quickly than non-gamers do.

The research is in Human Movement Science. (full access paywall)

Research: “The effect of action video game playing on sensorimotor learning: Evidence from a movement tracking task” by Gozli DG, Bavelier D, and Pratt J in Human Movement Science. doi:10.1016/j.humov.2014.09.004

Image: Researchers wanted to test whether the superior performance of gamers was as a result of learning rather than having better sensorimotor control. This image is for illustrative purposes only and shows people playing Call of Duty at a gaming convention. Credit PopCultureGeek.

#neuroscience   #gaming  ___

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2014-10-17 20:30:54 (1 comments, 9 reshares, 27 +1s)Open 

Scientists Develop Decoy Drug to Aid Ailing Brain

Full article at http://neurosciencenews.com/neurogenesis-visual-neuroscience-synapses-1449.

A team of Stanford Bio-X scientists has restored the ability of adult mice to form new connections in the brain. If the finding works in people, it has the potential to help adults recover from stroke and forms of blindness or to prevent the loss of connections in Alzheimer’s disease.

The research is in Science Translational Medicine. (full access paywall)

Research: “Blocking PirB up-regulates spines and functional synapses to unlock visual cortical plasticity and facilitate recovery from amblyopia” by David N. Bochner, Richard W. Sapp, Jaimie D. Adelson, Siyu Zhang, Hanmi Lee, Maja Djurisic, Josh Syken, Yang Dan, and Carla J. Shatz in Science Translational Medicine. doi:10.1126/scitranslmed.3010157... more »

Scientists Develop Decoy Drug to Aid Ailing Brain

Full article at http://neurosciencenews.com/neurogenesis-visual-neuroscience-synapses-1449.

A team of Stanford Bio-X scientists has restored the ability of adult mice to form new connections in the brain. If the finding works in people, it has the potential to help adults recover from stroke and forms of blindness or to prevent the loss of connections in Alzheimer’s disease.

The research is in Science Translational Medicine. (full access paywall)

Research: “Blocking PirB up-regulates spines and functional synapses to unlock visual cortical plasticity and facilitate recovery from amblyopia” by David N. Bochner, Richard W. Sapp, Jaimie D. Adelson, Siyu Zhang, Hanmi Lee, Maja Djurisic, Josh Syken, Yang Dan, and Carla J. Shatz in Science Translational Medicine. doi:10.1126/scitranslmed.3010157

Image: Researchers in Stanford’s Bio-X program are investigating growth in the neurons involved in a mouse’s visual system. Credit Maja Djurisic.

#neuroscience   #neurogenesis  ___

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2014-10-16 21:43:32 (5 comments, 8 reshares, 22 +1s)Open 

Are Male Brains Wired to Ignore Food for Sex?

Full article at http://neurosciencenews.com/neuroscience-sex-feeding-neural-network-1448.

Choosing between two good things can be tough. When animals must decide between feeding and mating, it can get even trickier. In a discovery that might ring true even for some humans, researchers have shown that male brains – at least in nematodes – will suppress the ability to locate food in order to instead focus on finding a mate.

The research is in Current Biology. (full access paywall)

Research: “Sex, Age, and Hunger Regulate Behavioral Prioritization through Dynamic Modulation of Chemoreceptor Expression” by Deborah A. Ryan, Renee M. Miller, KyungHwa Lee, Scott J. Neal, Kelli A. Fagan, Piali Sengupta, and Douglas S. Portman in Current Biology. doi:10.1016/j.cub.2014.09.032

Image: C.elegans... more »

Are Male Brains Wired to Ignore Food for Sex?

Full article at http://neurosciencenews.com/neuroscience-sex-feeding-neural-network-1448.

Choosing between two good things can be tough. When animals must decide between feeding and mating, it can get even trickier. In a discovery that might ring true even for some humans, researchers have shown that male brains – at least in nematodes – will suppress the ability to locate food in order to instead focus on finding a mate.

The research is in Current Biology. (full access paywall)

Research: “Sex, Age, and Hunger Regulate Behavioral Prioritization through Dynamic Modulation of Chemoreceptor Expression” by Deborah A. Ryan, Renee M. Miller, KyungHwa Lee, Scott J. Neal, Kelli A. Fagan, Piali Sengupta, and Douglas S. Portman in Current Biology. doi:10.1016/j.cub.2014.09.032

Image: C. elegans male (top) and hermaphrodite (bottom). Credit University of Rochester.

#neuroscience   #biology  ___

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2014-10-16 21:06:40 (1 comments, 5 reshares, 10 +1s)Open 

New Front in War on Alzheimer's and Other Protein Folding Diseases

Full article at http://neurosciencenews.com/alzheimers-genetics-hsf-1-chaperones-1447.

A surprise discovery that overturns decades of thinking about how the body fixes proteins that come unraveled greatly expands opportunities for therapies to prevent diseases such as Alzheimer’s and Parkinson’s, which have been linked to the accumulation of improperly folded proteins in the brain.

The research is in Science. (full access paywall)

Research: “HSF-1–mediated cytoskeletal integrity determines thermotolerance and life span” by Nathan A. Baird, Peter M. Douglas, Milos S. Simic, Ana R. Grant, James J. Moresco, Suzanne C. Wolff, John R. Yates III, Gerard Manning, and Andrew Dillin in Science.  doi:10.1126/science.1253168

*Image:*A cell suffering heat shock is like acountry be... more »

New Front in War on Alzheimer's and Other Protein Folding Diseases

Full article at http://neurosciencenews.com/alzheimers-genetics-hsf-1-chaperones-1447.

A surprise discovery that overturns decades of thinking about how the body fixes proteins that come unraveled greatly expands opportunities for therapies to prevent diseases such as Alzheimer’s and Parkinson’s, which have been linked to the accumulation of improperly folded proteins in the brain.

The research is in Science. (full access paywall)

Research: “HSF-1–mediated cytoskeletal integrity determines thermotolerance and life span” by Nathan A. Baird, Peter M. Douglas, Milos S. Simic, Ana R. Grant, James J. Moresco, Suzanne C. Wolff, John R. Yates III, Gerard Manning, and Andrew Dillin in Science.  doi:10.1126/science.1253168

*Image:*A cell suffering heat shock is like a country besieged, where attackers first sever lines of communications. The pat-10 gene helps repair communication to allow chaperones to treat misfolded proteins. Credit Andrew Dillin.

#alzheimersdisease   #genetics   #neuroscience  ___

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2014-10-16 20:20:31 (0 comments, 4 reshares, 13 +1s)Open 

Misfolded Proteins Clump Together in a Surprising Place

Full article at http://neurosciencenews.com/protein-aggregation-parkinsons-genetics-1446.

Scientists at the Stowers Institute for Medical Research have made a surprising finding about the aggregates of misfolded cellular proteins that have been linked to aging-related disorders such as Parkinson’s disease.

The research is in Cell. (full access paywall)

Research: “Organelle-Based Aggregation and Retention of Damaged Proteins in Asymmetrically Dividing Cells” by Chuankai Zhou, Brian D. Slaughter, Jay R. Unruh, Fengli Guo, Zulin Yu, Kristen Mickey, Akshay Narkar, Rhonda Trimble Ross, Melainia McClain, and Rong Li in Cell. doi:10.1016/j.cell.2014.09.026

Image: Left: Aggregates (green) bind to mitochondria (red). Right: Aggregates (green) bind to endoplasmic reticulum (red).Credi... more »

Misfolded Proteins Clump Together in a Surprising Place

Full article at http://neurosciencenews.com/protein-aggregation-parkinsons-genetics-1446.

Scientists at the Stowers Institute for Medical Research have made a surprising finding about the aggregates of misfolded cellular proteins that have been linked to aging-related disorders such as Parkinson’s disease.

The research is in Cell. (full access paywall)

Research: “Organelle-Based Aggregation and Retention of Damaged Proteins in Asymmetrically Dividing Cells” by Chuankai Zhou, Brian D. Slaughter, Jay R. Unruh, Fengli Guo, Zulin Yu, Kristen Mickey, Akshay Narkar, Rhonda Trimble Ross, Melainia McClain, and Rong Li in Cell. doi:10.1016/j.cell.2014.09.026

Image: Left: Aggregates (green) bind to mitochondria (red). Right: Aggregates (green) bind to endoplasmic reticulum (red). Credit Chaunkai Zhou, Rong Li Lab, Stowers Institute for Medical Research.

#genetics   #parkinsons   #neuroscience  ___

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2014-10-16 19:35:52 (0 comments, 4 reshares, 13 +1s)Open 

Myelin Vital for Learning New Practical Skills

Full article at http://neurosciencenews.com/myelin-learning-neuroscience-1445.

New evidence of myelin’s essential role in learning and retaining new practical skills, such as playing a musical instrument, has been uncovered by UCL research. Myelin is a fatty substance that insulates the brain’s wiring and is a major constituent of ‘white matter’. It is produced by the brain and spinal cord into early adulthood as it is needed for many developmental processes, and although earlier studies of human white matter hinted at its involvement in skill learning, this is the first time it has been confirmed experimentally.

The research is in Science. (full access paywall)

Research: “Motor skill learning requires active central myelination” by Ian A. McKenzie, David Ohayon, Huiliang Li, Joana Paes de Faria,Ben Emery, ... more »

Myelin Vital for Learning New Practical Skills

Full article at http://neurosciencenews.com/myelin-learning-neuroscience-1445.

New evidence of myelin’s essential role in learning and retaining new practical skills, such as playing a musical instrument, has been uncovered by UCL research. Myelin is a fatty substance that insulates the brain’s wiring and is a major constituent of ‘white matter’. It is produced by the brain and spinal cord into early adulthood as it is needed for many developmental processes, and although earlier studies of human white matter hinted at its involvement in skill learning, this is the first time it has been confirmed experimentally.

The research is in Science. (full access paywall)

Research: “Motor skill learning requires active central myelination” by Ian A. McKenzie, David Ohayon, Huiliang Li, Joana Paes de Faria, Ben Emery, Koujiro Tohyama, and William D. Richardson in Science. doi:10.1126/science.1254960

Image: Image shows the complex shape of individual oligodendrocytes (OLs) and myelin in adult mice injected with tamoxifen. OLs formed before tamoxifen injection are red, newly-forming OLs have a yellow ‘cell body’ containing the nucleus surrounded by a green ‘bundle of sticks’ which are short stretches of myelin wrapped around thread-like axons. Axons are not visible but there are many of them running across the image right to left. Credit Sarah Jolly, UCL.

#neuroscience   #myelin   #learning  ___

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2014-10-16 19:04:07 (3 comments, 20 reshares, 34 +1s)Open 

Scientists Find ‘Hidden Brain Signatures’ of Consciousness in Vegetative State Patients

Full article at http://neurosciencenews.com/neuroimaging-consciousness-vegetative-state-1444.

Scientists in Cambridge have found hidden signatures in the brains of people in a vegetative state, which point to networks that could support consciousness even when a patient appears to be unconscious and unresponsive. The study could help doctors identify patients who are aware despite being unable to communicate.

The research is in PLOS Computational Biology. (full open access)

Research: “Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness” by Srivas Chennu, Paola Finoia, Evelyn Kamau, Judith Allanson, Guy B. Williams, Martin M. Monti, Valdas Noreika, Aurina Arnatkeviciute, Andrés Canales-Johnson, Francisco Olivares, DanielaCabezas-... more »

Scientists Find ‘Hidden Brain Signatures’ of Consciousness in Vegetative State Patients

Full article at http://neurosciencenews.com/neuroimaging-consciousness-vegetative-state-1444.

Scientists in Cambridge have found hidden signatures in the brains of people in a vegetative state, which point to networks that could support consciousness even when a patient appears to be unconscious and unresponsive. The study could help doctors identify patients who are aware despite being unable to communicate.

The research is in PLOS Computational Biology. (full open access)

Research: “Spectral Signatures of Reorganised Brain Networks in Disorders of Consciousness” by Srivas Chennu, Paola Finoia, Evelyn Kamau, Judith Allanson, Guy B. Williams, Martin M. Monti, Valdas Noreika, Aurina Arnatkeviciute, Andrés Canales-Johnson, Francisco Olivares, Daniela Cabezas-Soto, David K. Menon, John D. Pickard, Adrian M. Owen, and Tristan A. Bekinschtein in PLOS Computational Biology. doi:10.1371/journal.pcbi.1003887

Image: These images show brain networks in two behaviorally similar vegetative patients (left and middle), but one of whom imagined playing tennis (middle panel), alongside a healthy adult (right panel). Credit Srivas Chennu.

#neuroscience   #neurology   #consciousness  ___

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2014-10-16 01:15:18 (1 comments, 9 reshares, 30 +1s)Open 

Brain’s Compass Relies on Geometric Relationships

Full article at http://neurosciencenews.com/geomatory-spatial-memory-orientation-1443.

The brain has a complex system for keeping track of which direction you are facing as you move about; remembering how to get from one place to another would otherwise be impossible. Researchers from the University of Pennsylvania have now shown how the brain anchors this mental compass.

The research is in Nature Neuroscience. (full access paywall)

Research: “Anchoring the neural compass: coding of local spatial reference frames in human medial parietal lobe” by Steven A Marchette, Lindsay K Vass, Jack Ryan and Russell A Epstein in Nature Neuroscience. doi:10.1038/nn.3834

Image: Each of the virtual museums in the study was visually distinct, but had the same layout and geometry. CreditUnive... more »

Brain’s Compass Relies on Geometric Relationships

Full article at http://neurosciencenews.com/geomatory-spatial-memory-orientation-1443.

The brain has a complex system for keeping track of which direction you are facing as you move about; remembering how to get from one place to another would otherwise be impossible. Researchers from the University of Pennsylvania have now shown how the brain anchors this mental compass.

The research is in Nature Neuroscience. (full access paywall)

Research: “Anchoring the neural compass: coding of local spatial reference frames in human medial parietal lobe” by Steven A Marchette, Lindsay K Vass, Jack Ryan and Russell A Epstein in Nature Neuroscience. doi:10.1038/nn.3834

Image: Each of the virtual museums in the study was visually distinct, but had the same layout and geometry. Credit University of Pennsylvania.

#neuroscience   #geometry   #memory  ___

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2014-10-16 00:29:48 (1 comments, 7 reshares, 15 +1s)Open 

Siblings of Children with Autism Can Show Signs at 18 Months

Full article at http://neurosciencenews.com/sibling-autism-genetics-1442.

About 20% of younger siblings of children with Autism Spectrum Disorder (ASD) will develop the condition by age 3. A new study by Yale School of Medicine researchers has found that 57% of these younger siblings who later develop the condition already showed symptoms at age 18 months.

The research is in Journal of the American Academy of Child & Adolescent Psychiatry. (full access paywall)

Research: “18-Month Predictors of Later Outcomes in Younger Siblings of Children With Autism Spectrum Disorder: A Baby Siblings Research Consortium Study” by Katarzyna Chawarska, Frederick Shic, Suzanne Macari, Daniel J. Campbell, Jessica Brian, Rebecca Landa, Ted Hutman, Charles A. Nelson, Sally Ozonoff, HelenTag... more »

Siblings of Children with Autism Can Show Signs at 18 Months

Full article at http://neurosciencenews.com/sibling-autism-genetics-1442.

About 20% of younger siblings of children with Autism Spectrum Disorder (ASD) will develop the condition by age 3. A new study by Yale School of Medicine researchers has found that 57% of these younger siblings who later develop the condition already showed symptoms at age 18 months.

The research is in Journal of the American Academy of Child & Adolescent Psychiatry. (full access paywall)

Research: “18-Month Predictors of Later Outcomes in Younger Siblings of Children With Autism Spectrum Disorder: A Baby Siblings Research Consortium Study” by Katarzyna Chawarska, Frederick Shic, Suzanne Macari, Daniel J. Campbell, Jessica Brian, Rebecca Landa, Ted Hutman, Charles A. Nelson, Sally Ozonoff, Helen Tager-Flusberg, Gregory S. Young, Lonnie Zwaigenbaum, Ira L. Cohen, Tony Charman, Daniel S. Messinger, Ami Klin, Scott Johnson, and Susan Bryson in Journal of the American Academy of Child & Adolescent Psychiatry. doi:10.1016/j.jaac.2014.09.015

Image: The team closely examined social, communicative, and repetitive behaviors in 719 infants when they were 18 months old. The team looked for patterns that might predict a later diagnosis of ASD. They then followed up when the participants were age 3. This image is for illustrative purposes only. Credit Columbia University School of Nursing / CTRPhotos.

#neuroscience   #autism   #genetics  ___

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2014-10-16 00:01:21 (0 comments, 6 reshares, 13 +1s)Open 

Effects of High Risk Parkinson’s Mutation Are Reversible

Full article at http://neurosciencenews.com/parkinsons-genetic-mutation-reversed-1441.

Researchers from the University of Sheffield have found vital new evidence on how to target and reverse the effects caused by one of the most common genetic causes of Parkinson’s.

The research is in Nature Communications. (full access paywall)

Research: “Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by ​LRRK2 Roc-COR domain mutations” by Vinay K. Godena, Nicholas Brookes-Hocking, Annekathrin Moller, Gary Shaw, Matthew Oswald, Rosa M. Sancho, Christopher C. J. Miller, Alexander J. Whitworth and Kurt J. De Vos in Nature Communications. doi:10.1038/ncomms6245

Image: A microscope image of a cultured cell. Credit University of Sheffield.
... more »

Effects of High Risk Parkinson’s Mutation Are Reversible

Full article at http://neurosciencenews.com/parkinsons-genetic-mutation-reversed-1441.

Researchers from the University of Sheffield have found vital new evidence on how to target and reverse the effects caused by one of the most common genetic causes of Parkinson’s.

The research is in Nature Communications. (full access paywall)

Research: “Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by ​LRRK2 Roc-COR domain mutations” by Vinay K. Godena, Nicholas Brookes-Hocking, Annekathrin Moller, Gary Shaw, Matthew Oswald, Rosa M. Sancho, Christopher C. J. Miller, Alexander J. Whitworth and Kurt J. De Vos in Nature Communications. doi:10.1038/ncomms6245

Image: A microscope image of a cultured cell. Credit University of Sheffield.

#neurology   #genetics   #parkinsonsdisease  ___

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2014-10-15 23:26:35 (2 comments, 5 reshares, 16 +1s)Open 

Heroes Don’t Deliberate Before They Act

Full article at http://neurosciencenews.com/alturism-heroism-psychology-1440.

People who risk their lives to save strangers do so without deliberation, according to a Yale-led analysis of statements from more than 50 recognized civilian heroes.

The research is in PLOS ONE. (full open access)

Research: “Risking Your Life without a Second Thought: Intuitive Decision-Making and Extreme Altruism” by David G. Rand and Ziv G. Epstein in PLOS ONE. doi:10.1371/journal.pone.0109687 (http://dx.doi.org/10.1038/mp.2014.118)

Image: Researchers recruited hundreds of participants to read 51 statements made by individuals who have received the Carnegie Hero Medal, given to civilians who risk their lives to save strangers. Participants analyzed those statements for evidence of whether they actedintui... more »

Heroes Don’t Deliberate Before They Act

Full article at http://neurosciencenews.com/alturism-heroism-psychology-1440.

People who risk their lives to save strangers do so without deliberation, according to a Yale-led analysis of statements from more than 50 recognized civilian heroes.

The research is in PLOS ONE. (full open access)

Research: “Risking Your Life without a Second Thought: Intuitive Decision-Making and Extreme Altruism” by David G. Rand and Ziv G. Epstein in PLOS ONE. doi:10.1371/journal.pone.0109687 (http://dx.doi.org/10.1038/mp.2014.118)

Image: Researchers recruited hundreds of participants to read 51 statements made by individuals who have received the Carnegie Hero Medal, given to civilians who risk their lives to save strangers. Participants analyzed those statements for evidence of whether they acted intuitively or with deliberation. An analysis of text by computer algorithm did the same. Credit Yale.

#psychology   #altruism  ___

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2014-10-15 22:45:37 (0 comments, 7 reshares, 12 +1s)Open 

Taking a Shot at Parkinson’s

Full article at http://neurosciencenews.com/dopamine-stem-cells-parkisons-1439.

Just one shot of dopamine cells derived from stem cells could be enough to reverse many of the features of Parkinson’s disease for decades – and the barriers to developing such a treatment are finally being overcome.

Image: Neurons from a human neural stem cell. Credit Wellcome Trust.

Taking a Shot at Parkinson’s

Full article at http://neurosciencenews.com/dopamine-stem-cells-parkisons-1439.

Just one shot of dopamine cells derived from stem cells could be enough to reverse many of the features of Parkinson’s disease for decades – and the barriers to developing such a treatment are finally being overcome.

Image: Neurons from a human neural stem cell. Credit Wellcome Trust.___

posted image

2014-10-15 22:02:32 (8 comments, 6 reshares, 17 +1s)Open 

Brain Surgery Through the Cheek

Full article at http://neurosciencenews.com/robotics-neurosurgery-hippocampus-1438.

For those most severely affected, treating epilepsy means drilling through the skull deep into the brain to destroy the small area where the seizures originate – invasive, dangerous and with a long recovery period.

Image: Patient mockup of surgical robot designed to treat epilepsy by entering the brain through the cheek. Credit Laboratory for the Design and Control of Energetic Systems / Vanderbilt.

#robotics   #neurosurgery   #neuroscience  

Brain Surgery Through the Cheek

Full article at http://neurosciencenews.com/robotics-neurosurgery-hippocampus-1438.

For those most severely affected, treating epilepsy means drilling through the skull deep into the brain to destroy the small area where the seizures originate – invasive, dangerous and with a long recovery period.

Image: Patient mockup of surgical robot designed to treat epilepsy by entering the brain through the cheek. Credit Laboratory for the Design and Control of Energetic Systems / Vanderbilt.

#robotics   #neurosurgery   #neuroscience  ___

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2014-10-14 22:11:25 (1 comments, 10 reshares, 22 +1s)Open 

Rare Genetic Disease Protects Against Bipolar Disorder

Full article at http://neurosciencenews.com/evc-genetics-bipolar-psychology-1437.

A team of scientists led by researchers at the UMass Medical School and the University of Miami Miller School of Medicine (UMMSM) have identified what is likely a key genetic pathway underlying bipolar disorder, a breakthrough that could lead to better drugs for treating bipolar affective disorder, as well as depression and other related mood disorders.

The research is in Molecular Psychiatry. (full access paywall)

Research: “Disruption of sonic hedgehog signaling in Ellis-van Creveld dwarfism confers protection against bipolar affective disorder” by E I Ginns, M Galdzicka, R C Elston, Y E Song, S M Paul and J A Egeland in Molecular Psychiatry. doi:10.1038/mp.2014.118

*Image:*EvC dwarfism results fromgen... more »

Rare Genetic Disease Protects Against Bipolar Disorder

Full article at http://neurosciencenews.com/evc-genetics-bipolar-psychology-1437.

A team of scientists led by researchers at the UMass Medical School and the University of Miami Miller School of Medicine (UMMSM) have identified what is likely a key genetic pathway underlying bipolar disorder, a breakthrough that could lead to better drugs for treating bipolar affective disorder, as well as depression and other related mood disorders.

The research is in Molecular Psychiatry. (full access paywall)

Research: “Disruption of sonic hedgehog signaling in Ellis-van Creveld dwarfism confers protection against bipolar affective disorder” by E I Ginns, M Galdzicka, R C Elston, Y E Song, S M Paul and J A Egeland in Molecular Psychiatry. doi:10.1038/mp.2014.118

*Image:*EvC dwarfism results from genetic mutations that disrupt the signaling pathway known as sonic hedgehog (Shh). Statistical analyses confirmed the significant negative association between EvC and bipolar disorder. This further suggested that the Shh pathway plays a role in bipolar disorder. This image is for illustrative purposes only and shows the 3D structure of the Sonic Hedgehog protein. Credit Peter Znamenskiy/ Hall et al.

#psychology   #genetics   #bipolardisorder  ___

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2014-10-14 21:35:46 (0 comments, 4 reshares, 16 +1s)Open 

Microrobots Armed with New Force-Sensing System to Probe Cells

Full article at http://neurosciencenews.com/microbot-force-sensing-cellular-research-1436.

Inexpensive microrobots capable of probing and manipulating individual cells and tissue for biological research and medical applications are closer to reality with the design of a system that senses the minute forces exerted by a robot’s tiny probe.

The research is in Robotics. (full open access)

Research: “A Magnetic Microrobot with in situ Force Sensing Capabilities” by Wuming Jing and David Cappelleri in Robotics. doi:10.3390/robotics3020106

Image: This image shows a “microforce-sensing mobile microrobot” juxtaposed against a U.S. penny. The device is being developed at Purdue University. Credit Purdue.

#robotics   #bioengineering   #technology  

Microrobots Armed with New Force-Sensing System to Probe Cells

Full article at http://neurosciencenews.com/microbot-force-sensing-cellular-research-1436.

Inexpensive microrobots capable of probing and manipulating individual cells and tissue for biological research and medical applications are closer to reality with the design of a system that senses the minute forces exerted by a robot’s tiny probe.

The research is in Robotics. (full open access)

Research: “A Magnetic Microrobot with in situ Force Sensing Capabilities” by Wuming Jing and David Cappelleri in Robotics. doi:10.3390/robotics3020106

Image: This image shows a “microforce-sensing mobile microrobot” juxtaposed against a U.S. penny. The device is being developed at Purdue University. Credit Purdue.

#robotics   #bioengineering   #technology  ___

posted image

2014-10-14 20:50:00 (1 comments, 4 reshares, 14 +1s)Open 

Orphanage Care Linked to Thinner Brain Tissue in Regions Related to ADHD

Full article at http://neurosciencenews.com/mri-orphan-adhd-cortex-psychology-1435.

University of Washington research on children who began life in orphanages shows that early childhood neglect is associated with changes in brain structure.

The research is in Biological Psychiatry. (full access paywall)

Research: “Widespread Reductions in Cortical Thickness Following Severe Early-Life Deprivation: A Neurodevelopmental Pathway to Attention-Deficit/Hyperactivity Disorder” by SKatie A. McLaughlin, Margaret A. Sheridan, Warren Winter, Nathan A. Fox, Charles H. Zeanah, and Charles A. Nelson in Biological Psychiatry. doi:10.1016/j.biopsych.2013.08.016

Image: Differences in the thickness of the cortex in institutionalized children. All differences show thinningcom... more »

Orphanage Care Linked to Thinner Brain Tissue in Regions Related to ADHD

Full article at http://neurosciencenews.com/mri-orphan-adhd-cortex-psychology-1435.

University of Washington research on children who began life in orphanages shows that early childhood neglect is associated with changes in brain structure.

The research is in Biological Psychiatry. (full access paywall)

Research: “Widespread Reductions in Cortical Thickness Following Severe Early-Life Deprivation: A Neurodevelopmental Pathway to Attention-Deficit/Hyperactivity Disorder” by SKatie A. McLaughlin, Margaret A. Sheridan, Warren Winter, Nathan A. Fox, Charles H. Zeanah, and Charles A. Nelson in Biological Psychiatry. doi:10.1016/j.biopsych.2013.08.016

Image: Differences in the thickness of the cortex in institutionalized children. All differences show thinning compared to children raised in a home. Credit K. McLaughlin / UW.

#adhd   #neuroimaging   #psychology  ___

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2014-10-14 19:57:06 (2 comments, 17 reshares, 32 +1s)Open 

New Study Finds That Neurons Actively 'Fine Tune' Themselves at the Genetic Level

Full article at http://neurosciencenews.com/mrna-ion-channels-cluster-neurons-1434.

A new study provides the first biological evidence that neurons are finely “tuning” their own molecular-level machinery to regulate this flow of ions and thus their electrical charge.

The research is in Current Biology. (full access paywall)

Research: “Activity-Dependent Feedback Regulates Correlated Ion Channel mRNA Levels in Single Identified Motor Neurons” by Simone Temporal, Kawasi M. Lett, and David J. Schulz in Current Biology. doi:10.1016/j.cub.2014.06.067

Image: The researchers tested their hypothesis using a cluster of neurons called the stomatogastric ganglion that is at the center of a network of nerves and muscles that helps process food inthe Jon... more »

New Study Finds That Neurons Actively 'Fine Tune' Themselves at the Genetic Level

Full article at http://neurosciencenews.com/mrna-ion-channels-cluster-neurons-1434.

A new study provides the first biological evidence that neurons are finely “tuning” their own molecular-level machinery to regulate this flow of ions and thus their electrical charge.

The research is in Current Biology. (full access paywall)

Research: “Activity-Dependent Feedback Regulates Correlated Ion Channel mRNA Levels in Single Identified Motor Neurons” by Simone Temporal, Kawasi M. Lett, and David J. Schulz in Current Biology. doi:10.1016/j.cub.2014.06.067

Image: The researchers tested their hypothesis using a cluster of neurons called the stomatogastric ganglion that is at the center of a network of nerves and muscles that helps process food in the Jonah crab. This image is for illustrative purposes only and shows the stomatogastric ganglion of a Jonah crab. This image is not connected to the research. Credit Wstein.

#neuroscience  ___

posted image

2014-10-14 19:17:45 (1 comments, 4 reshares, 15 +1s)Open 

Damage to Brain ‘Hubs’ Causes Extensive Impairment

Full article at http://neurosciencenews.com/neural-networks-injury-brain-impairment-1433.

Injuries to six brain areas are much more devastating to patients’ abilities to think and adapt to everyday challenges than damage to other parts of the brain, scientists at Washington University School of Medicine in St. Louis have learned.

The research is in PNAS. (full access paywall)

Research: “Network measures predict neuropsychological outcome after brain injury” by David E. Warren, Jonathan D. Power, Joel Bruss, Natalie L. Denburg, Eric J. Waldron, Haoxin Sun, Steven E. Petersen, and Daniel Tranel in PNAS. doi:10.1073/pnas.1322173111

Image: Colors illustrate different networks of the brain. Researchers have discovered that injuries to a brain hub (top), where the boundaries ofseveral n... more »

Damage to Brain ‘Hubs’ Causes Extensive Impairment

Full article at http://neurosciencenews.com/neural-networks-injury-brain-impairment-1433.

Injuries to six brain areas are much more devastating to patients’ abilities to think and adapt to everyday challenges than damage to other parts of the brain, scientists at Washington University School of Medicine in St. Louis have learned.

The research is in PNAS. (full access paywall)

Research: “Network measures predict neuropsychological outcome after brain injury” by David E. Warren, Jonathan D. Power, Joel Bruss, Natalie L. Denburg, Eric J. Waldron, Haoxin Sun, Steven E. Petersen, and Daniel Tranel in PNAS. doi:10.1073/pnas.1322173111

Image: Colors illustrate different networks of the brain. Researchers have discovered that injuries to a brain hub (top), where the boundaries of several networks come together, can be much more devastating than similar injuries in other parts of the brain (bottom). Credit Steven E. Petersen.

#neuroscience   #braininjury  ___

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