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Shared Circles including Daniel Lemire

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The Google+ Collections of Daniel Lemire

Activity

Average numbers for the latest posts (max. 50 posts, posted within the last 4 weeks)

5
comments per post
2
reshares per post
12
+1's per post

192
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Top posts in the last 50 posts

Most comments: 44

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2016-01-18 15:56:37 (44 comments; 1 reshares; 7 +1s)Open 

Yes. You are just an ordinary biological robot. Sometimes you break down. Sometimes you work well. But it is just Physics. No room for free will or consciousness or magic pixies...

Most reshares: 22

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2016-01-05 16:09:38 (4 comments; 22 reshares; 55 +1s)Open 

First human trials to deliver cancer drugs using programmable nanorobots... 

Most plusones: 55

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2016-01-05 16:09:38 (4 comments; 22 reshares; 55 +1s)Open 

First human trials to deliver cancer drugs using programmable nanorobots... 

Latest 50 posts

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2016-02-10 18:56:08 (0 comments; 0 reshares; 3 +1s)Open 

Editing can help build stronger muscles: Gene editing improved skeletal muscle function. http://science.sciencemag.org/content/351/6271/407.abstract

Editing can help build stronger muscles: Gene editing improved skeletal muscle function. http://science.sciencemag.org/content/351/6271/407.abstract___

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2016-02-09 23:24:40 (1 comments; 4 reshares; 25 +1s)Open 

Wheelchair-bound multiple sclerosis patients able to walk again after stem-cell therapy http://www.telegraph.co.uk/news/health/12104774/Miraculous-results-from-new-MS-treatment.html

Wheelchair-bound multiple sclerosis patients able to walk again after stem-cell therapy http://www.telegraph.co.uk/news/health/12104774/Miraculous-results-from-new-MS-treatment.html___

2016-02-09 19:44:42 (16 comments; 0 reshares; 4 +1s)Open 

I have been looking for a new laptop for my wife, and I am surprised to notice that most vendors sell their laptops with spinning drives.

I realize that SSDs are more expensive and smaller, but for most people, it is probably the priority, far above getting a "6th generation Intel core processor". 

I have been looking for a new laptop for my wife, and I am surprised to notice that most vendors sell their laptops with spinning drives.

I realize that SSDs are more expensive and smaller, but for most people, it is probably the priority, far above getting a "6th generation Intel core processor". ___

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2016-02-08 23:20:34 (1 comments; 0 reshares; 12 +1s)Open 

Dell sells servers with 6 TB of RAM:
http://www.dell.com/us/business/p/poweredge-r920/pd

Dell sells servers with 6 TB of RAM:
http://www.dell.com/us/business/p/poweredge-r920/pd___

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2016-02-08 17:18:14 (0 comments; 1 reshares; 1 +1s)Open 

___

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2016-02-03 23:16:59 (10 comments; 13 reshares; 44 +1s)Open 

Mayo Clinic scientists have radically extended the the lifespan of mice—and humans are next 

Mayo Clinic scientists have radically extended the the lifespan of mice—and humans are next ___

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2016-02-02 16:07:19 (2 comments; 1 reshares; 18 +1s)Open 

According to the BBC, UK scientists will soon be altering the DNA of human embryos. http://www.bbc.com/news/health-35459054

According to the BBC, UK scientists will soon be altering the DNA of human embryos. http://www.bbc.com/news/health-35459054___

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2016-02-01 22:32:56 (9 comments; 1 reshares; 5 +1s)Open 

___

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2016-02-01 15:17:18 (2 comments; 1 reshares; 5 +1s)Open 

Here is an important argument in favour of convenient automated access to the scientific literature: once you have that, you can use machine learning to understand what is happening...

"The results from two large-scale experiments with 3.8 million full-text articles and 48 million metadata records support the conclusion that full-text features are significantly more useful for prediction than metadata-only features and that the most accurate predictions result from combining the metadata and full-text features. "

http://onlinelibrary.wiley.com/doi/10.1002/asi.23612/abstract

Here is an important argument in favour of convenient automated access to the scientific literature: once you have that, you can use machine learning to understand what is happening...

"The results from two large-scale experiments with 3.8 million full-text articles and 48 million metadata records support the conclusion that full-text features are significantly more useful for prediction than metadata-only features and that the most accurate predictions result from combining the metadata and full-text features. "

http://onlinelibrary.wiley.com/doi/10.1002/asi.23612/abstract___

2016-01-28 15:51:09 (0 comments; 0 reshares; 5 +1s)Open 

External-Memory Sorting in Java : useful to sort very large files. https://github.com/lemire/externalsortinginjava

External-Memory Sorting in Java : useful to sort very large files. https://github.com/lemire/externalsortinginjava___

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2016-01-27 23:50:37 (11 comments; 0 reshares; 16 +1s)Open 

___

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2016-01-27 15:36:34 (0 comments; 2 reshares; 13 +1s)Open 

Telomerase therapies to prevent and treat age-related diseases (open access paper by M. Blasco) 

Telomerase therapies to prevent and treat age-related diseases (open access paper by M. Blasco) ___

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2016-01-27 15:05:42 (0 comments; 3 reshares; 19 +1s)Open 

Beyond drugs...

Beyond drugs...___

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2016-01-26 15:28:24 (7 comments; 2 reshares; 1 +1s)Open 

How much trust are you supposed to give a peer-reviewed article? 

How much trust are you supposed to give a peer-reviewed article? ___

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2016-01-25 15:36:05 (2 comments; 3 reshares; 31 +1s)Open 

Some ants do not "age" (Reminder: not all living organisms age like we do.)

Some ants do not "age" (Reminder: not all living organisms age like we do.)___

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2016-01-25 14:51:08 (0 comments; 1 reshares; 5 +1s)Open 

Vernor Vinge is a master of scifi literature. In 2015, I reviewed some of the predictions his book Rainbows End made for 2025. I continue my review...

Vernor Vinge is a master of scifi literature. In 2015, I reviewed some of the predictions his book Rainbows End made for 2025. I continue my review...___

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2016-01-22 20:02:01 (2 comments; 1 reshares; 10 +1s)Open 

Neil deGrasse Tyson vs. Ray Kurzweil On The Singularity

Neil deGrasse Tyson vs. Ray Kurzweil On The Singularity___

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2016-01-21 16:38:20 (0 comments; 2 reshares; 5 +1s)Open 

"Lab-grown neural networks have the ability to replace lost axonal tracks in the brains of patients with severe head injuries, strokes or neurodegenerative diseases and can be safely delivered with minimal disruption to brain tissue,"

http://www.uphs.upenn.edu/news/News_Releases/2016/01/cullen/

"Lab-grown neural networks have the ability to replace lost axonal tracks in the brains of patients with severe head injuries, strokes or neurodegenerative diseases and can be safely delivered with minimal disruption to brain tissue,"

http://www.uphs.upenn.edu/news/News_Releases/2016/01/cullen/___

2016-01-21 14:56:29 (0 comments; 0 reshares; 5 +1s)Open 

Reliably reprogramming your cells so that they change their type

http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3487.html

Reliably reprogramming your cells so that they change their type

http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3487.html___

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2016-01-20 19:24:27 (1 comments; 0 reshares; 15 +1s)Open 

« Those born today have a chance of living to 150, and lifespans of 120 years may well be the norm. Your marriage had better be good if it is to last a century.
"We are not talking about something ridiculously ambitious or unrealistic or visionary," said Dr Elizabeth Blackburn, who won the Nobel Prize in 2009 for research on telomeres and the genetics of ageing.»
http://www.telegraph.co.uk/finance/financetopics/davos/12111287/Nobel-scientist-tells-us-we-can-live-to-150.html

« Those born today have a chance of living to 150, and lifespans of 120 years may well be the norm. Your marriage had better be good if it is to last a century.
"We are not talking about something ridiculously ambitious or unrealistic or visionary," said Dr Elizabeth Blackburn, who won the Nobel Prize in 2009 for research on telomeres and the genetics of ageing.»
http://www.telegraph.co.uk/finance/financetopics/davos/12111287/Nobel-scientist-tells-us-we-can-live-to-150.html___

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2016-01-19 17:04:22 (2 comments; 2 reshares; 20 +1s)Open 

Stem cell therapies have dramatically improved the lives of people with Multiple Sclerosis 

Stem cell therapies have dramatically improved the lives of people with Multiple Sclerosis ___

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2016-01-18 15:56:37 (44 comments; 1 reshares; 7 +1s)Open 

Yes. You are just an ordinary biological robot. Sometimes you break down. Sometimes you work well. But it is just Physics. No room for free will or consciousness or magic pixies...

Yes. You are just an ordinary biological robot. Sometimes you break down. Sometimes you work well. But it is just Physics. No room for free will or consciousness or magic pixies...___

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2016-01-17 18:49:00 (0 comments; 1 reshares; 12 +1s)Open 

(Speculative) The right mix of signals could rejuvenate your stem cells and reverse some of aging...

(Speculative) The right mix of signals could rejuvenate your stem cells and reverse some of aging...___

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2016-01-15 14:33:47 (4 comments; 5 reshares; 16 +1s)Open 

Efforts to better target cancer therapy.... reduce the toxicity 50x for the same cancer killing effects... http://uncnews.unc.edu/2016/01/14/unc-chapel-hill-researchers-kill-drug-resistant-lung-cancer-with-50-times-less-chemo/

Efforts to better target cancer therapy.... reduce the toxicity 50x for the same cancer killing effects... http://uncnews.unc.edu/2016/01/14/unc-chapel-hill-researchers-kill-drug-resistant-lung-cancer-with-50-times-less-chemo/___

2016-01-14 23:05:47 (0 comments; 2 reshares; 13 +1s)Open 

23% drop in the cancer death rate since its peak in 1991 http://pressroom.cancer.org/Cancer-Stats2016

23% drop in the cancer death rate since its peak in 1991 http://pressroom.cancer.org/Cancer-Stats2016___

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2016-01-13 16:32:01 (2 comments; 2 reshares; 22 +1s)Open 

We might soon be able to "industrialize" stem-cell production to help regenerate tissues economically and safely. Here is more work in this direction.

We might soon be able to "industrialize" stem-cell production to help regenerate tissues economically and safely. Here is more work in this direction.___

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2016-01-12 19:51:26 (4 comments; 0 reshares; 13 +1s)Open 

Fun thought experiments.

Fun thought experiments.___

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2016-01-12 14:34:05 (1 comments; 6 reshares; 24 +1s)Open 

It looks like the FGF21 hormone would be anti-aging (showing 40% life extension in mice). Specifically, it seems to protect and boost the thymus, an important gland that trains immune cells (T cells). As you get older, you thymus disappears, it is mostly gone by the time you are 40, which leads to an incompetent immune system in old age. We could check whether elevating FGF21 pharmacologically could extend the human healthspan and boost immune function.


It looks like the FGF21 hormone would be anti-aging (showing 40% life extension in mice). Specifically, it seems to protect and boost the thymus, an important gland that trains immune cells (T cells). As you get older, you thymus disappears, it is mostly gone by the time you are 40, which leads to an incompetent immune system in old age. We could check whether elevating FGF21 pharmacologically could extend the human healthspan and boost immune function.
___

2016-01-11 20:47:02 (1 comments; 1 reshares; 5 +1s)Open 

Lots of big money invested in a speculative technique that might detect cancers early using blood or urine.

Lots of big money invested in a speculative technique that might detect cancers early using blood or urine.___

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2016-01-11 16:28:27 (2 comments; 1 reshares; 5 +1s)Open 

Revisiting a 20-year-old scifi novel... (edit: it is Bruce Sterling and not Sterlin, obviously)

Revisiting a 20-year-old scifi novel... (edit: it is Bruce Sterling and not Sterlin, obviously)___

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2016-01-09 01:35:08 (3 comments; 1 reshares; 12 +1s)Open 

Can AI Master Eighth-grade Science? It seems it can.

Can AI Master Eighth-grade Science? It seems it can.___

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2016-01-08 23:29:37 (5 comments; 9 reshares; 19 +1s)Open 

We have no clue how to even just slow down Alzheimer's right now... despite billions spent in research money. Other neurodegenerative diseases like Parkinson's are in no better shape. Yet if you live long enough, then you have a 50%-50% chance of getting some form of dementia. Some people think that the key to an Alzheimer's therapy could be to reduce brain inflammation. It is quite speculative however. 

We have no clue how to even just slow down Alzheimer's right now... despite billions spent in research money. Other neurodegenerative diseases like Parkinson's are in no better shape. Yet if you live long enough, then you have a 50%-50% chance of getting some form of dementia. Some people think that the key to an Alzheimer's therapy could be to reduce brain inflammation. It is quite speculative however. ___

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2016-01-06 16:09:14 (6 comments; 13 reshares; 25 +1s)Open 

In 2014, in the states of Colorado, Utah, Virginia and Washington, the most common job was software programmer. 

In 2014, in the states of Colorado, Utah, Virginia and Washington, the most common job was software programmer. ___

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2016-01-06 14:06:56 (0 comments; 0 reshares; 6 +1s)Open 

There are many ways to boost your cognitive skills. Staying fit is one of them. Climbing trees is probably great for your brain. "Brain games" in general, however, do not have a good scientific track record.


There are many ways to boost your cognitive skills. Staying fit is one of them. Climbing trees is probably great for your brain. "Brain games" in general, however, do not have a good scientific track record.
___

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2016-01-05 21:04:01 (1 comments; 1 reshares; 20 +1s)Open 

In What does technology want?, +Kevin Kelly argued that technology is on an evolutionary path. In some real sense, technology is alive and growing. It seeks out to improve itself at an ever faster rate. And it seems that technology currently loves software.

The difference between a recent processor and a processor from 10 years ago is ~10x. Yet it is not like Google is the same as it was, except 10x faster. Without better software, our video games would be like old-school Pac-Man, except that they would run at 1 million frames per second. If that sounds ridiculous, that’s because it is: software has improved thousandfolds.

I don’t think we are going to see an evil artificial intelligence trying to enslave us in the coming decades. However, we are going to get seriously insane software. It is not going to look like what we have today, only faster. It is probably unimaginable rightnow... more »

In What does technology want?, +Kevin Kelly argued that technology is on an evolutionary path. In some real sense, technology is alive and growing. It seeks out to improve itself at an ever faster rate. And it seems that technology currently loves software.

The difference between a recent processor and a processor from 10 years ago is ~10x. Yet it is not like Google is the same as it was, except 10x faster. Without better software, our video games would be like old-school Pac-Man, except that they would run at 1 million frames per second. If that sounds ridiculous, that’s because it is: software has improved thousandfolds.

I don’t think we are going to see an evil artificial intelligence trying to enslave us in the coming decades. However, we are going to get seriously insane software. It is not going to look like what we have today, only faster. It is probably unimaginable right now.___

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2016-01-05 16:09:38 (4 comments; 22 reshares; 55 +1s)Open 

First human trials to deliver cancer drugs using programmable nanorobots... 

First human trials to deliver cancer drugs using programmable nanorobots... ___

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2016-01-05 16:05:50 (3 comments; 2 reshares; 10 +1s)Open 

These people are very optimistic about printing human body parts (cartilage for now) http://www.bbc.com/news/uk-wales-south-west-wales-35140916

These people are very optimistic about printing human body parts (cartilage for now) http://www.bbc.com/news/uk-wales-south-west-wales-35140916___

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2016-01-01 16:22:30 (6 comments; 4 reshares; 27 +1s)Open 

Ending 2015 with yet another breakthrough medical advance enabled by CRISPR technology. 

"The red-hot genome editing tool known as CRISPR has scored another achievement: Researchers have used it to treat a severe form of muscular dystrophy in mice. Three groups report today in Science that they wielded CRISPR to snip out part of a defective gene in mice with Duchenne muscular dystrophy (DMD), allowing the animals to make an essential muscle protein. The approach is the first time CRISPR has been successfully delivered throughout the body to treat grown animals with a genetic disease."

Ending 2015 with yet another breakthrough medical advance enabled by CRISPR technology. 

"The red-hot genome editing tool known as CRISPR has scored another achievement: Researchers have used it to treat a severe form of muscular dystrophy in mice. Three groups report today in Science that they wielded CRISPR to snip out part of a defective gene in mice with Duchenne muscular dystrophy (DMD), allowing the animals to make an essential muscle protein. The approach is the first time CRISPR has been successfully delivered throughout the body to treat grown animals with a genetic disease."___

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2015-12-30 21:24:05 (0 comments; 11 reshares; 27 +1s)Open 

Soon, your watch will have more data about your health than your doctor. 

Soon, your watch will have more data about your health than your doctor. ___

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2015-12-30 15:33:47 (1 comments; 1 reshares; 3 +1s)Open 

I continue to review my most popular posts for this year... (part 2 of 2)

I continue to review my most popular posts for this year... (part 2 of 2)___

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2015-12-29 15:09:37 (7 comments; 3 reshares; 16 +1s)Open 

As you age, your muscle mass and strength diminish. Weak muscles are a risk factor for many illnesses. Thankfully, we think we know one practical way on how to reverse this particular age-related condition: myostatin inhibition. And there is an ongoing clinical trial now that looks very promising. Muscle rejuvenation is, indeed, around the corner. 

As you age, your muscle mass and strength diminish. Weak muscles are a risk factor for many illnesses. Thankfully, we think we know one practical way on how to reverse this particular age-related condition: myostatin inhibition. And there is an ongoing clinical trial now that looks very promising. Muscle rejuvenation is, indeed, around the corner. ___

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2015-12-28 20:03:01 (5 comments; 2 reshares; 15 +1s)Open 

For 100k$, you can get a clone of your dead dog. (The cost could probably go down quite a bit.)

For 100k$, you can get a clone of your dead dog. (The cost could probably go down quite a bit.)___

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2015-12-28 15:22:18 (0 comments; 3 reshares; 1 +1s)Open 

I am starting a two-part series reviewing the most popular posts from my blog in 2015.

I am starting a two-part series reviewing the most popular posts from my blog in 2015.___

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2015-12-28 14:25:31 (0 comments; 1 reshares; 13 +1s)Open 

What happened in 2015 according to Bill Gates? No polio case in Africa. The Americas have eliminated Rubella. Plus a few minor things. I think that there was more good news in 2015 but that's a start...

What happened in 2015 according to Bill Gates? No polio case in Africa. The Americas have eliminated Rubella. Plus a few minor things. I think that there was more good news in 2015 but that's a start...___

2015-12-24 18:49:42 (0 comments; 0 reshares; 1 +1s)Open 

Your software should follow your hardware: the CLHash example http://lemire.me/blog/2015/12/24/your-software-should-follow-your-hardware-the-clhash-example/

Your software should follow your hardware: the CLHash example http://lemire.me/blog/2015/12/24/your-software-should-follow-your-hardware-the-clhash-example/___

2015-12-24 16:16:55 (9 comments; 0 reshares; 0 +1s)Open 

What are the languages supporting binary literals (0b011)? So far I have: Python, Java, C/C++… 

What are the languages supporting binary literals (0b011)? So far I have: Python, Java, C/C++… ___

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2015-12-23 22:59:07 (3 comments; 4 reshares; 27 +1s)Open 

We have more polar bears... global warming has not killed them yet.

We have more polar bears... global warming has not killed them yet.___

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2015-12-22 16:54:11 (0 comments; 1 reshares; 7 +1s)Open 

biofilms are extremely tough to get rid of, so this is very welcome news.

biofilms are extremely tough to get rid of, so this is very welcome news.___

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2015-12-22 16:03:50 (5 comments; 3 reshares; 19 +1s)Open 

The key to progress is to have courage to face what we do not understand.

The key to progress is to have courage to face what we do not understand.___

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2015-12-21 16:42:12 (0 comments; 0 reshares; 8 +1s)Open 

The more fantasy we allow, the more progress we enable, the more fantasy it creates...

The more fantasy we allow, the more progress we enable, the more fantasy it creates...___

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